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15 records found for search term Xrn1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1309713Xrn15'-3' exoribonuclease 1ENCODES a protein that exhibits 5'-3' RNA exonuclease activity (ortholog); G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide; cellular response to puromycin; negative regulation of translation; PARTICIPATES IN ribosome biogenesis8105407785105516967Rat121symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1332329Xrn15'-3' exoribonuclease 1Enables 5'-3' RNA exonuclease activity; G-quadruplex DNA binding activity; and G-quadruplex RNA binding activity. Predicted to be involved in RNA catabolic process and negative regulation of translation. Located in P-body. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous99583680395939859Mouse149symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1348971XRN15'-3' exoribonuclease 1This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a3142306610142448037Human132symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8816666Xrn15'-3' exoribonuclease 1ENCODES a protein that exhibits 5'-3' RNA exonuclease activity (ortholog); G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); histone mRNA catabolic process (ortholog); ASSOCINW_00495550834415403561896Chinchilla34symbolgene, protein-coding, MODEL [RefSeq]
11861671XRN15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog3139337337139481479Bonobo50symbolgene, protein-coding, MODEL [RefSeq]
12161732XRN15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog233803163338131413Dog50symbolgene, protein-coding, MODEL [RefSeq]
12619658Xrn15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Alzheimer's disease (orthologNW_00493654039591564073785Squirrel50symbolgene, protein-coding, MODEL [RefSeq]
14254393XRN15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Alzheimer's disease (orthologPig50symbolgene, protein-coding, MODEL [RefSeq]
18924672Xrn15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); telomerase RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); histone mRNA catabolic process (ortholog); ASSOCIATED WITNaked Mole-Rat47symbolgene, protein-coding, MODEL [RefSeq]
155234970xrn1Tropical Clawed Frogsymbolgene, null
18377128XRN15'-3' exoribonuclease 1ENCODES a protein that exhibits G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH Alzheimer's disease (orthologGreen Monkey50symbolgene, protein-coding, MODEL [RefSeq]
626008838Xrn15'-3' exoribonuclease 1ENCODES a protein that exhibits 5'-3' RNA exonuclease activity (ortholog); G-quadruplex DNA binding (ortholog); G-quadruplex RNA binding (ortholog); INVOLVED IN cellular response to cycloheximide (ortholog); cellular response to puromycin (ortholog); histone mRNA catabolic process (ortholog); ASSOCIBlack Rat34symbolgene, protein-coding, MODEL [RefSeq]
14389204XRN1Yeastsymbolgene, null
155234969xrn1.LAfrican Clawed Frogsymbolgene, null
155258514xrn1.SAfrican Clawed Frogsymbolgene, null