| 1306493 | Dync2i1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein light chain binding (ortholog); INVOLVED IN cilium assembly (ortholog); embryonic skeletal system morphogenesis (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (ortholog); ciliary base (ortholog); cilium (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 6 | 143276441 | 143333006 | Rat | 94 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1315142 | Dync2i1 | dynein 2 intermediate chain 1 | Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in intraciliary retrograde transport. Located in cilium. Is expressed in mandible; maxilla; olfactory epithelium; and orbito-sphenoid. Human ortholog(s) of this gene implicated i n short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2025] | 12 | 116169881 | 116226665 | Mouse | 114 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605671 | DYNC2I1 | dynein 2 intermediate chain 1 | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014] | 7 | 158839245 | 158958698 | Human | 244 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8791703 | Dync2i1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein light chain binding (ortholog); INVOLVED IN cilium assembly (ortholog); embryonic skeletal system morphogenesis (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (ortholog); ciliary base (ortholog); cilium (ortholog) | NW_004955579 | 1056291 | 1124623 | Chinchilla | 26 | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12099336 | DYNC2I1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein heavy chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); embryonic skeletal system morphogenesis (inferred); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog ); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (inferred); ciliary base (inferred); cilium (inferred) | 16 | 20810735 | 20859441 | Dog | 40 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12552570 | Dync2i1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein heavy chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); embryonic skeletal system morphogenesis (inferred); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog ); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (inferred); ciliary base (inferred); cilium (inferred) | NW_004936856 | 724863 | 792490 | Squirrel | 32 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907747 | Dync2i1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein heavy chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN cilium assembly (ortholog); embryonic skeletal system morphogenesis (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ort holog); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN ciliary base (ortholog); interphase microtubule organizing center (ortholog); pericentriolar material (ortholog) | | | | Naked Mole-Rat | 30 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14145712 | DYNC2I1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein heavy chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); embryonic skeletal system morphogenesis (inferred); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog ); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (inferred); ciliary base (inferred); cilium (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 40 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18659568 | DYNC2I1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein light chain binding (ortholog); INVOLVED IN cilium assembly (ortholog); embryonic skeletal system morphogenesis (ortholog); intraciliary retrograde transport (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (ortholog); ciliary base (ortholog); cilium (ortholog) | | | | Green Monkey | 26 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11693211 | DYNC2I1 | dynein 2 intermediate chain 1 | ENCODES a protein that exhibits dynein heavy chain binding (inferred); dynein light chain binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); embryonic skeletal system morphogenesis (inferred); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog ); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN centrosome (inferred); ciliary base (inferred); cilium (inferred) | | | | Bonobo | 32 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |