| 619940 | Vcan | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine phosphatase activator activity (ortholog); INVOLVED IN axon regeneration; glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH myocardial infarction; Myocardial Reperfusion Injury; aden oid cystic carcinoma (ortholog); FOUND IN cell surface; extracellular matrix; perineuronal net; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 22497035 | 22595955 | Rat | 275 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731396 | Vcan | versican | Enables protein phosphatase binding activity. Involved in ureteric bud development. Acts upstream of or within heart development. Located in extracellular matrix. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart; and jaw. Human orth olog(s) of this gene implicated in intracranial aneurysm. Orthologous to human VCAN (versican). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 89803429 | 89891146 | Mouse | 330 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1349729 | VCAN | versican | This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a ce ntral role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] | 5 | 83471744 | 83582302 | Human | 494 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8930472 | Vcan | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine phosphatase activator activity (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); extracellular region (ortholog) | NW_004955418 | 26967595 | 27078430 | Chinchilla | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11867349 | VCAN | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN ce ll surface (ortholog); extracellular matrix (ortholog); perineuronal net (ortholog) | 5 | 31699278 | 31810169 | Bonobo | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12094994 | VCAN | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN ce ll surface (ortholog); extracellular matrix (ortholog); perineuronal net (ortholog) | 3 | 24127293 | 24238859 | Dog | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12566576 | Vcan | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN ce ll surface (ortholog); extracellular matrix (ortholog); perineuronal net (ortholog) | NW_004936469 | 2585142 | 2688029 | Squirrel | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18906528 | Vcan | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine phosphatase activator activity (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); extracellular region (ortholog) | | | | Naked Mole-Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18766886 | VCAN | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN ce ll surface (ortholog); extracellular matrix (ortholog); perineuronal net (ortholog) | | | | Green Monkey | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234705 | vcan | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626046957 | Vcan | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); protein tyrosine phosphatase activator activity (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); extracellular region (ortholog) | | | | Black Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14092801 | VCAN | versican | ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN axon regeneration (ortholog); glial cell migration (ortholog); heart development (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN ce ll surface (ortholog); extracellular matrix (ortholog); perineuronal net (ortholog); INTERACTS WITH 4-methylumbelliferone | | | | Pig | 60 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155234704 | vcan.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626174115 | vcan.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6481395 | VCAN-AS1 | VCAN antisense RNA 1 | ASSOCIATED WITH genetic disease; prostate cancer; INTERACTS WITH aristolochic acid A; doxorubicin | 5 | 83531352 | 83562314 | Human | 5 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |