| 1311555 | Usp28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Pros tatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-hydroxyisovaleric acid | 8 | 58222258 | 58282711 | Rat | 121 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323075 | USP28 | ubiquitin specific peptidase 28 | The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016] | 11 | 113797875 | 113875572 | Human | 123 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1323076 | Usp28 | ubiquitin specific peptidase 28 | Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including intracellular signal transduction; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Predicted to be located in nu clear body. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in early embryo; foregut; heart; and skeletal musculature. Orthologous to human USP28 (ubiquitin specific peptidase 28). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 48896577 | 48953817 | Mouse | 127 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8857549 | Usp28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Pros tatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog) | NW_004955412 | 15425136 | 15469819 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12049548 | USP28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); protein-containing complex (ortholog) | 11 | 108676566 | 108754372 | Bonobo | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12353544 | USP28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); protein-containing complex (ortholog) | 5 | 19431313 | 19480709 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12463503 | Usp28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); protein-containing complex (ortholog) | NW_004936612 | 742777 | 804919 | Squirrel | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907158 | Usp28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); DNA damage response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13998659 | USP28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); protein-containing complex (ortholog) | | | | Pig | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626144265 | Usp28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Pros tatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18463517 | USP28 | ubiquitin specific peptidase 28 | ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); ASSOCIATED WITH prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nuclear body (ortholog); protein-containing complex (ortholog) | | | | Green Monkey | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238363 | usp28 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155258358 | usp28.L | | | | | | African Clawed Frog | | symbol | gene, null |