Usp28 (ubiquitin specific peptidase 28) - Rat Genome Database

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Gene: Usp28 (ubiquitin specific peptidase 28) Ictidomys tridecemlineatus
Analyze
Symbol: Usp28
Name: ubiquitin specific peptidase 28
RGD ID: 12463503
Description: ENCODES a protein that exhibits deubiquitinase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to UV (ortholog); DNA damage response (ortholog); ASSOCIATED WITH chromosome 11 partial duplication syndrome (ortholog); intellectual disability (ortholog); prostate cancer (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 28
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612742,725 - 804,921 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Usp28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612742,725 - 804,921 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811113,797,875 - 113,875,572 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11113,797,874 - 113,875,572 (-)EnsemblGRCh38hg38GRCh38
GRCh3711113,668,597 - 113,746,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,173,807 - 113,251,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411113,173,807 - 113,251,466NCBI
Celera11110,821,475 - 110,899,132 (-)NCBICelera
Cytogenetic Map11q23.2NCBI
HuRef11109,597,124 - 109,674,696 (-)NCBIHuRef
CHM1_111113,551,888 - 113,629,830 (-)NCBICHM1_1
T2T-CHM13v2.011113,808,211 - 113,885,899 (-)NCBIT2T-CHM13v2.0
Usp28
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39948,896,577 - 48,953,817 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl948,896,675 - 48,953,817 (+)EnsemblGRCm39 Ensembl
GRCm38948,985,319 - 49,042,517 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl948,985,375 - 49,042,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37948,793,490 - 48,850,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36948,737,317 - 48,794,449 (+)NCBIMGSCv36mm8
Celera946,282,655 - 46,339,797 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.56NCBI
Usp28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,222,258 - 58,282,711 (+)NCBIGRCr8
mRatBN7.2849,325,766 - 49,386,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,325,867 - 49,386,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,831,791 - 54,892,095 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,110,659 - 53,170,968 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0850,974,908 - 51,035,219 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,295,188 - 53,355,572 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,295,222 - 53,355,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,909,256 - 51,969,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,245,642 - 52,305,922 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,280,014 - 52,324,051 (+)NCBI
Celera848,883,162 - 48,943,411 (+)NCBICelera
Cytogenetic Map8q23NCBI
Usp28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,426,159 - 15,443,023 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,425,136 - 15,469,819 (-)NCBIChiLan1.0ChiLan1.0
USP28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,541,035 - 114,618,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,635,396 - 115,713,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,676,566 - 108,754,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,519,147 - 112,595,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,517,693 - 112,595,585 (-)Ensemblpanpan1.1panPan2
USP28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,431,313 - 19,480,709 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,435,451 - 19,479,640 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,338,576 - 19,404,153 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0519,435,675 - 19,501,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl519,437,389 - 19,501,355 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1519,499,600 - 19,565,243 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0519,400,925 - 19,465,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0519,448,052 - 19,514,120 (+)NCBIUU_Cfam_GSD_1.0
USP28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,417,564 - 41,480,994 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,417,560 - 41,481,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2946,178,504 - 46,217,852 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11105,175,116 - 105,257,163 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1105,175,067 - 105,257,102 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604320,764,288 - 20,844,351 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247849,303,745 - 9,378,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247849,302,741 - 9,352,127 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000008839   ⟹   ENSSTOP00000007920
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936612742,725 - 804,921 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000034441   ⟹   ENSSTOP00000030989
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936612742,881 - 803,883 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000042313   ⟹   ENSSTOP00000025968
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936612742,725 - 804,921 (+)Ensembl
RefSeq Acc Id: XM_005334203   ⟹   XP_005334260
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005334204   ⟹   XP_005334261
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,847 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732360   ⟹   XP_021588035
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732362   ⟹   XP_021588037
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732363   ⟹   XP_021588038
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,847 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732365   ⟹   XP_021588040
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,847 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732366   ⟹   XP_021588041
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,847 (-)NCBI
SpeTri2.0NW_004936612742,777 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732368   ⟹   XP_021588043
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,831 (-)NCBI
SpeTri2.0NW_004936612742,824 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732369   ⟹   XP_021588044
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,830 (-)NCBI
SpeTri2.0NW_004936612742,824 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732370   ⟹   XP_021588045
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,939,963 (-)NCBI
SpeTri2.0NW_004936612765,646 - 804,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040285240   ⟹   XP_040141174
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,962,410 (-)NCBI
RefSeq Acc Id: XM_040285241   ⟹   XP_040141175
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,900,690 - 95,939,877 (-)NCBI
RefSeq Acc Id: XP_005334260   ⟸   XM_005334203
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005334261   ⟸   XM_005334204
- Peptide Label: isoform X6
- UniProtKB: I3MCD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021588037   ⟸   XM_021732362
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021588040   ⟸   XM_021732365
- Peptide Label: isoform X7
- UniProtKB: A0A287DBT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021588038   ⟸   XM_021732363
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021588035   ⟸   XM_021732360
- Peptide Label: isoform X2
- UniProtKB: A0A287CXG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021588041   ⟸   XM_021732366
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_021588043   ⟸   XM_021732368
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_021588044   ⟸   XM_021732369
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_021588045   ⟸   XM_021732370
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_040141174   ⟸   XM_040285240
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040141175   ⟸   XM_040285241
- Peptide Label: isoform X9
Ensembl Acc Id: ENSSTOP00000025968   ⟸   ENSSTOT00000042313
Ensembl Acc Id: ENSSTOP00000030989   ⟸   ENSSTOT00000034441
Ensembl Acc Id: ENSSTOP00000007920   ⟸   ENSSTOT00000008839
Protein Domains
USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008820 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008839.3 UniProtKB/TrEMBL
  ENSSTOT00000034441.1 UniProtKB/TrEMBL
  ENSSTOT00000042313.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.1720 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  USP25/28_UIM UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
NCBI Gene Usp28 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 UniProtKB/TrEMBL
Pfam UBA_8 UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  USP_UIM_N UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A287CXG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DBT2 ENTREZGENE, UniProtKB/TrEMBL
  I3MCD9 ENTREZGENE, UniProtKB/TrEMBL