| 1308361 | Ube2l3 | ubiquitin-conjugating enzyme E2L 3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocortic oid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; Parkinson's disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN presynapse; cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 97300584 | 97343084 | Rat | 136 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318085 | UBE2L3 | ubiquitin conjugating enzyme E2 L3 | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein liga ses (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009] | 22 | 21549447 | 21624034 | Human | 204 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1557759 | Ube2l3 | ubiquitin-conjugating enzyme E2L 3 | Enables ubiquitin conjugating enzyme activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; heart; immune system; lung; and reproductive system. Orthologous to several human genes including UBE2L3 (ubiquitin conjugating enzyme E2 L3). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 16969879 | 17019363 | Mouse | 161 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8796933 | Ube2l3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocortic oid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | NW_004955442 | 17487815 | 17581675 | Chinchilla | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11771813 | UBE2L3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activator activity (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocorticoid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | 22 | 3690100 | 3746665 | Bonobo | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12314617 | UBE2L3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activator activity (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocorticoid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | 26 | 30835222 | 30899842 | Dog | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12614198 | Ube2l3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transcription coactivator activity (inferred); INVOLVED IN obsolete positive regulation of protein targeting to mitochondrion (ortholog); ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN m itochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN presynapse (ortholog) | NW_004936619 | 2070836 | 2137314 | Squirrel | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13897919 | UBE2L3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activator activity (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocorticoid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | | | | Pig | 47 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155244950 | ube2l3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626143504 | Ube2l3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocortic oid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | | | | Black Rat | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932336 | Ube2l3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activator activity (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocorticoid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | | | | Naked Mole-Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18707987 | UBE2L3 | ubiquitin conjugating enzyme E2 L3 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cell cycle phase transition (ortholog); cell population proliferation (ortholog); cellular response to glucocortic oid stimulus (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Chronic Hepatitis B (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); presynapse (ortholog) | | | | Green Monkey | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231890 | ube2l3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155237940 | ube2l3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1588178 | Ube2l3-ps1 | ubiquitin-conjugating enzyme E2L 3, pseudogene 1 | | X | 113405094 | 113405546 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1620869 | Ube2l3-ps1 | ubiquitin-conjugating enzyme E2L 3, pseudogene 1 | | 3 | 35600024 | 35600697 | Mouse | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 9474148 | Ube2l3-ps2 | ubiquitin-conjugating enzyme E2L 3, pseudogene 2 | | X | 46908414 | 46908868 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41391875 | Ube2l3-ps3 | ubiquitin-conjugating enzyme E2L 3, pseudogene 3 | | 2 | 13370376 | 13371194 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 38669644 | UBE2L3P1 | UBE2L3 pseudogene 1 | | 4 | 62292016 | 62292334 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 625776960 | UBE2L3P2 | UBE2L3 pseudogene 2 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38673862 | UBE2L3P3 | UBE2L3 pseudogene 3 | | 14 | 76013648 | 76014334 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16561745 | AC008015.1 | ubiquitin-conjugating enzyme E2L 3 (UBE2L3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16566046 | AC013244.3 | ubiquitin-conjugating enzyme E2L 3 (UBE2L3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16560027 | AC018861.1 | ubiquitin-conjugating enzyme E2L 3 (UBE2L3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16558799 | AC105313.1 | ubiquitin-conjugating enzyme E2L 3 (UBE2L3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16569094 | AL158801.4 | ubiquitin-conjugating enzyme E2L 3 (UBE2L3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1317456 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein liga ses (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011] | 11 | 57551662 | 57567935 | Human | 178 | description | gene, protein-coding, REVIEWED [RefSeq] |