| 1343102 | TMIE | transmembrane inner ear | This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndro mic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq, Mar 2009] | 3 | 46693778 | 46710886 | Human | 106 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1562523 | Tmie | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH 2,3,7, 8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 8 | 119728123 | 119743219 | Rat | 76 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1614414 | Tmie | transmembrane inner ear | Acts upstream of or within inner ear morphogenesis and sensory perception of sound. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 6 and sensorineural hearing loss. Orthologous to human TMIE >TMIE (transmembrane inner ear). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 110694755 | 110709141 | Mouse | 104 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8865972 | Tmie | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | NW_004955420 | 25428542 | 25435701 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12274590 | TMIE | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | 20 | 42052607 | 42061424 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12562195 | Tmie | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | NW_004936596 | 531260 | 540608 | Squirrel | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 32728424 | TMIE | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | 3 | 46590527 | 46608981 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909840 | Tmie | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867218 | TMIE | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (inferred); sensory perception of sound (inferred) | | | | Green Monkey | 2 | symbol | gene, protein-coding |
| 286753565 | tmie | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626003153 | Tmie | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14215553 | TMIE | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 14 | symbol | gene, ncrna, MODEL [RefSeq] |
| 18666731 | TMIE | transmembrane inner ear | INVOLVED IN inner ear morphogenesis (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 6 (ortholog); genetic disease (ortholog) | | | | Green Monkey | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 287066509 | tmie.L | | | | | | African Clawed Frog | | symbol | gene, null |