| 1359736 | Tmem98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (ortholog); negative regulation of oligodendrocyte differentiation (ortholog); negative regulation of protein localization to nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (ort holog); endoplasmic reticulum membrane (ortholog); extracellular exosome (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 66293895 | 66304806 | Rat | 135 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1607062 | TMEM98 | transmembrane protein 98 | This gene encodes a transmembrane protein. A missense mutation in this gene result in Nanophthalmos 4 (NNO4). Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2014] | 17 | 32928153 | 32944315 | Human | 130 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1615770 | Tmem98 | transmembrane protein 98 | Involved in several processes, including T-helper 1 cell differentiation; negative regulation of protein processing; and regulation of nervous system development. Located in endoplasmic reticulum membrane and extracellular space. Is expressed in pigmented retinal epithelium; spinal cord; and white m atter. Human ortholog(s) of this gene implicated in nanophthalmos. Orthologous to human TMEM98 (transmembrane protein 98). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 80701192 | 80712859 | Mouse | 133 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8866135 | Tmem98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (ortholog); negative regulation of oligodendrocyte differentiation (ortholog); negative regulation of protein localization to nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (ort holog); endoplasmic reticulum membrane (ortholog); extracellular exosome (ortholog) | NW_004955481 | 7788066 | 7797433 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11830968 | TMEM98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (ortholog); negative regulation of oligodendrocyte differentiation (ortholog); negative regulation of protein localization to nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred) | 17 | 23844747 | 23858390 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12391874 | TMEM98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (inferred); negative regulation of oligodendrocyte differentiation (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred) | 9 | 40130421 | 40144120 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12517844 | Tmem98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (inferred); negative regulation of oligodendrocyte differentiation (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred) | NW_004936538 | 2065663 | 2074678 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14049829 | TMEM98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (inferred); negative regulation of oligodendrocyte differentiation (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred); INTERACTS WITH ethanol | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913419 | Tmem98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (inferred); negative regulation of oligodendrocyte differentiation (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18572439 | TMEM98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (inferred); negative regulation of oligodendrocyte differentiation (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (inf erred); endoplasmic reticulum membrane (inferred); extracellular exosome (inferred) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625973629 | Tmem98 | transmembrane protein 98 | INVOLVED IN negative regulation of myelination (ortholog); negative regulation of oligodendrocyte differentiation (ortholog); negative regulation of protein localization to nucleus (ortholog); ASSOCIATED WITH genetic disease (ortholog); Nanophthalmos 4 (ortholog); FOUND IN endoplasmic reticulum (ort holog); endoplasmic reticulum membrane (ortholog); extracellular exosome (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251719 | tmem98 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155258572 | tmem98.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155251718 | tmem98.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38634224 | TMEM98P1 | TMEM98 pseudogene 1 | | 14 | 58827482 | 58828516 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38673927 | TMEM98P2 | TMEM98 pseudogene 2 | | 6 | 64733002 | 64733893 | Human | | symbol , GTEx , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16561824 | AL049873.2 | transmembrane protein 98 (TMEM98) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16557814 | AL355357.1 | transmembrane protein 98 (TMEM98) pseudogene | | | | | Human | | name | gene, transcribed_processed_pseudogene |