| 708371 | Tmem33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (ortholog); positive regulation of PERK-mediated unfolded protein response (ortholog); regulation of endoplasmic reticulum tubular network organization (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticu lum membrane (ortholog); melanosome (ortholog); INTERACTS WITH 17beta-estradiol; acetamide; amitrole | 14 | 41242358 | 41264586 | Rat | 123 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733060 | Tmem33 | transmembrane protein 33 | Predicted to be involved in several processes, including endoplasmic reticulum tubular network organization; positive regulation of endoplasmic reticulum unfolded protein response; and regulation of endoplasmic reticulum tubular network organization. Predicted to be located in endoplasmic reticulum membrane; melanosome; and nuclear envelope. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including central nervous system; nasal cavity epithelium; retina; submandibular gland primordium; and trigeminal nerve. Orthologous to human TMEM33 (transmembrane protein 33). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 67417908 | 67448804 | Mouse | 122 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1353146 | TMEM33 | transmembrane protein 33 | Involved in positive regulation of endoplasmic reticulum unfolded protein response; regulation of endoplasmic reticulum tubular network organization; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum membrane; melanosome; and nuclear envelope. [provided by Alliance of Ge nome Resources, Jul 2025] | 4 | 41935137 | 41960803 | Human | 111 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 9040259 | Tmem33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (ortholog); positive regulation of PERK-mediated unfolded protein response (ortholog); regulation of endoplasmic reticulum tubular network organization (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticu lum membrane (ortholog); melanosome (ortholog) | NW_004955443 | 5747681 | 5773759 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12032264 | TMEM33 | transmembrane protein 33 | INVOLVED IN endoplasmic reticulum tubular network organization (inferred); membrane organization (inferred); positive regulation of IRE1-mediated unfolded protein response (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); melanosome (inferred) | 4 | 36260669 | 36281546 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12374149 | TMEM33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (inferred); positive regulation of PERK-mediated unfolded protein response (inferred); regulation of endoplasmic reticulum tubular network organization (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticu lum membrane (inferred); melanosome (inferred) | 13 | 39013799 | 39039059 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12499022 | Tmem33 | transmembrane protein 33 | INVOLVED IN endoplasmic reticulum tubular network organization (inferred); membrane organization (inferred); positive regulation of IRE1-mediated unfolded protein response (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); melanosome (inferred) | NW_004936482 | 9138752 | 9166555 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14004481 | TMEM33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (inferred); positive regulation of PERK-mediated unfolded protein response (inferred); regulation of endoplasmic reticulum tubular network organization (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticu lum membrane (inferred); melanosome (inferred); INTERACTS WITH ammonia | | | | Pig | 19 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 626089563 | Tmem33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (ortholog); positive regulation of PERK-mediated unfolded protein response (ortholog); regulation of endoplasmic reticulum tubular network organization (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticu lum membrane (ortholog); melanosome (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923988 | Tmem33 | transmembrane protein 33 | INVOLVED IN positive regulation of IRE1-mediated unfolded protein response (ortholog); positive regulation of PERK-mediated unfolded protein response (ortholog); regulation of endoplasmic reticulum tubular network organization (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); melanosom e (ortholog); nuclear envelope (ortholog) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18748219 | TMEM33 | transmembrane protein 33 | INVOLVED IN endoplasmic reticulum tubular network organization (inferred); membrane organization (inferred); positive regulation of IRE1-mediated unfolded protein response (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); melanosome (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242755 | tmem33 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155242754 | tmem33.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240309 | tmem33.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38617281 | TMEM33-DT | TMEM33 divergent transcript | | 4 | 41910447 | 41934675 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |