| 621778 | Stau1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding; protein phosphatase 1 binding; RNA binding (ortholog); INVOLVED IN cellular response to oxidative stress; modification of postsynaptic structure; modulation of chemical synaptic transmission; ASSOCIATED WITH atherosclerosis (ortholog); myo tonic disease (ortholog); FOUND IN glutamatergic synapse; neuronal cell body; cell body (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene | 3 | 176099053 | 176144947 | Rat | 129 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 734025 | STAU1 | staufen double-stranded RNA binding protein 1 | Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to b ind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020] | 20 | 49113339 | 49219295 | Human | 138 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 734026 | Stau1 | staufen double-stranded RNA binding protein 1 | Enables RNA binding activity. Involved in dendritic transport of messenger ribonucleoprotein complex. Acts upstream of or within intracellular mRNA localization. Located in cytoplasmic stress granule and neuron projection. Part of ribonucleoprotein complex. Is expressed in several structures, includ ing alimentary system; central nervous system; early conceptus; gonad; and sensory organ. Orthologous to human STAU1 (staufen double-stranded RNA binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 166789469 | 166838253 | Mouse | 121 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8979740 | Stau1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); RNA binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localizati on (ortholog); ASSOCIATED WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN cell body (ortholog); cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog) | NW_004955445 | 8971585 | 9003647 | Chinchilla | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12049594 | STAU1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); neuronal cell body (ortholog); ribonucleoprotein complex (ortholog) | 20 | 45452639 | 45526512 | Bonobo | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12385482 | STAU1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN cytoplasmic stress granule (ortholog); glutamatergic synapse (ortholog); neuronal cell body (ortholog) | 24 | 35816224 | 35868791 | Dog | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12443985 | Stau1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); neuronal cell body (ortholog); ribonucleoprotein complex (ortholog) | NW_004936514 | 5058682 | 5103493 | Squirrel | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900775 | Stau1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN cell body (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232130 | stau1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13954401 | STAU1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN cytoplasmic stress granule (ortholog); glutamatergic synapse (ortholog); neuronal cell body (ortholog) | | | | Pig | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626036908 | Stau1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); RNA binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localizati on (ortholog); ASSOCIATED WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN cell body (ortholog); cytoplasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog) | | | | Black Rat | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18698447 | STAU1 | staufen double-stranded RNA binding protein 1 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); dendritic transport of messenger ribonucleoprotein complex (ortholog); intracellular mRNA localization (ortholog); ASSOCIATE D WITH atherosclerosis (ortholog); myotonic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); neuronal cell body (ortholog); ribonucleoprotein complex (ortholog) | | | | Green Monkey | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248518 | stau1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155232129 | stau1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16565251 | AC011492.1 | staufen, RNA binding protein, homolog 1 (Drosophila) (STAU1) pseudogene | | 19 | 15515143 | 15516838 | Human | | name | gene, pseudo, INFERRED [RefSeq] |