Spred3 Gene Search Result

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14 records found for search term Spred3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1311713	Spred3	sprouty-related, EVH1 domain containing 3	INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); PARTICIPATES IN Jak-Stat signaling pathway; FOUND IN plasma membrane (ortholog); INTERACTS W ... (more) ITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; amphetamine	1	93586259	93597692	Rat	52	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1550004	Spred3	sprouty-related EVH1 domain containing 3	Predicted to enable protein kinase binding activity. Involved in negative regulation of cell differentiation and negative regulation of signal transduction. Acts upstream of or within negative regulation of MAPK cascade. Located in plasma membrane. Is expressed in several structures, including centr ... (more) al nervous system; dorsal root ganglion; extraembryonic component; and pancreas. Orthologous to human SPRED3 (sprouty related EVH1 domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]	7	28857208	28869286	Mouse	62	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1606081	SPRED3	sprouty related EVH1 domain containing 3	This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase ... (more) signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]	19	38388697	38399587	Human	50	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
8717328	Spred3	sprouty related EVH1 domain containing 3	INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); FOUND IN plasma membrane (ortholog)	NW_004955468	1030964	1039495	Chinchilla	6	symbol	gene, protein-coding, MODEL [RefSeq]
11978103	SPRED3	sprouty related EVH1 domain containing 3	ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); FOUND IN membrane (inferr ... (more) ed); plasma membrane (inferred)	19	35482436	35490745	Bonobo	11	symbol	gene, protein-coding, MODEL [RefSeq]
12091622	SPRED3	sprouty related EVH1 domain containing 3	INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of lens fiber cell differentiation (ortholog); negative regulation of MAPK cascade (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)	1	114604265	114614764	Dog	11	symbol	gene, protein-coding, MODEL [RefSeq]
12532333	Spred3	sprouty related EVH1 domain containing 3	ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN negative regulation of MAPK cascade (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)	NW_004936801	1150897	1160016	Squirrel	10	symbol	gene, protein-coding, MODEL [RefSeq]
18731774	SPRED3	sprouty related EVH1 domain containing 3	ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); FOUND IN membrane (inferr ... (more) ed); plasma membrane (inferred)				Green Monkey	11	symbol	gene, protein-coding, MODEL [RefSeq]
18927671	Spred3	sprouty related EVH1 domain containing 3	ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN negative regulation of MAPK cascade (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)				Naked Mole-Rat	11	symbol	gene, protein-coding, MODEL [RefSeq]
284511481	spred3						Tropical Clawed Frog		symbol	gene, null
14227914	SPRED3	sprouty related EVH1 domain containing 3	INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of lens fiber cell differentiation (ortholog); negative regulation of MAPK cascade (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol				Pig	12	symbol	gene, protein-coding, MODEL [RefSeq]
626013098	Spred3	sprouty related EVH1 domain containing 3	INVOLVED IN negative regulation of epithelial to mesenchymal transition (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of lens fiber cell differentiation (ortholog); FOUND IN plasma membrane (ortholog)				Black Rat	6	symbol	gene, protein-coding, MODEL [RefSeq]
287670464	spred3.L						African Clawed Frog		symbol	gene, null
287629033	spred3.S						African Clawed Frog		symbol	gene, null