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Gene: Spred3 (sprouty-related EVH1 domain containing 3) Mus musculus
Symbol: Spred3
Name: sprouty-related EVH1 domain containing 3
Description: Predicted to have protein kinase binding activity. Involved in inactivation of MAPK activity. Localizes to the plasma membrane. Is expressed in several structures, including central nervous system; dorsal root ganglion; extraembryonic component; and pancreas. Orthologous to human SPRED3 (sprouty related EVH1 domain containing 3); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; ethanol; troglitazone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW047143; D130060H24Rik; Spred-3; Sprouty-related EVH1 domain-containing protein; sprouty-related, EVH1 domain containing 3; sprouty-related, EVH1 domain-containing protein 3
Homo sapiens (human) : SPRED3 (sprouty related EVH1 domain containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spred3 (sprouty-related, EVH1 domain containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spred3 (sprouty related EVH1 domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRED3 (sprouty related EVH1 domain containing 3)
Canis lupus familiaris (dog) : SPRED3 (sprouty related EVH1 domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spred3 (sprouty related EVH1 domain containing 3)
Sus scrofa (pig) : SPRED3 (sprouty related EVH1 domain containing 3)
Chlorocebus sabaeus (green monkey) : SPRED3 (sprouty related EVH1 domain containing 3)
Heterocephalus glaber (naked mole-rat) : Spred3 (sprouty related EVH1 domain containing 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl729,158,829 - 29,170,411 (-)Ensembl
GRCm38729,157,783 - 29,170,070 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37729,943,848 - 29,953,666 (-)NCBIGRCm37mm9NCBIm37
MGSCv36728,867,589 - 28,877,407 (-)NCBImm8
Celera723,728,916 - 23,738,734 (-)NCBICelera
Cytogenetic Map7 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Spred3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550004
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.