| 1305672 | Spock3 | SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachloro dibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 16 | 31149698 | 31582280 | Rat | 71 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1313840 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively splice d transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] | 4 | 166733384 | 167234945 | Human | 79 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313841 | Spock3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 | Enables glycosaminoglycan binding activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space. Is expressed in central nervous system and retina. Orthologous to human SPOCK3 font-weight:700;'>SPOCK3 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 63404034 | 63810135 | Mouse | 83 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8742870 | Spock3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | NW_004955403 | 38476251 | 38870760 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12040597 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits calcium ion binding (inferred); collagen binding (inferred); enzyme inhibitor activity (inferred); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog) | 4 | 158941142 | 159437078 | Bonobo | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12340219 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits calcium ion binding (inferred); enzyme inhibitor activity (inferred); glycosaminoglycan binding (inferred); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | 15 | 62395713 | 62661308 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12619703 | Spock3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog) | NW_004936851 | 316979 | 443444 | Squirrel | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18343456 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits calcium ion binding (inferred); collagen binding (inferred); enzyme inhibitor activity (inferred); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog) | | | | Green Monkey | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20865905 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 625948243 | Spock3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259609 | spock3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14216208 | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18935588 | Spock3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | ENCODES a protein that exhibits metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of endopeptidase activity (ortholog); FOUND IN extracellular matrix (ortholog) | | | | Naked Mole-Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626182361 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856525 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859804 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865648 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626177439 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857898 | spock3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858317 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626179885 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626176012 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861006 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858659 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857780 | spock3.S | | | | | | African Clawed Frog | | symbol | gene, null |
