Sorcs3 Gene Search Result

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16 records found for search term Sorcs3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1310974	Sorcs3	sortilin-related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); positive regulation of synaptic transmission (ortholog); FOUND IN glutamatergic synapse (ortholog); plasma membrane (ortholog); postsynaptic density (ortholog); INTERACTS WITH 3,4-methylenedioxymethamphetamine; atrazine; bisphenol A	1	257040442	257675259	Rat	80	symbol , old_gene_name , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1322178	SORCS3	sortilin related VPS10 domain containing receptor 3	This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein con ... (more) vertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid precursor protein processing. [provided by RefSeq, Dec 2014]	10	104641290	105265242	Human	80	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1322179	Sorcs3	sortilin-related VPS10 domain containing receptor 3	Involved in postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within learning; memory; and regulation of long-term synaptic depression. Located in postsynaptic density. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structur ... (more) es, including brain; cochlea; genitourinary system; retina; and trigeminal ganglion. Orthologous to human SORCS3 (sortilin related VPS10 domain containing receptor 3). [provided by Alliance of Genome Resources, Apr 2025]	19	48194464	48793944	Mouse	80	symbol , old_gene_name , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8756240	Sorcs3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); positive regulation of synaptic transmission (ortholog); FOUND IN glutamatergic synapse (ortholog); plasma membrane (ortholog); postsynaptic density (ortholog)	NW_004955485	5474081	6048912	Chinchilla	14	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
11778013	SORCS3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); regulation of long-term synaptic depression (ortholog); FOUND IN glutamatergic synapse (inferred); membrane (inferred); plasma membrane (inferred)	10	101239765	101856507	Bonobo	20	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
12372724	SORCS3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); regulation of long-term synaptic depression (ortholog); FOUND IN glutamatergic synapse (inferred); membrane (inferred); plasma membrane (inferred)	28	16909908	17491097	Dog	21	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
155236210	sorcs3						Tropical Clawed Frog		symbol	gene, null
14232557	SORCS3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); regulation of long-term synaptic depression (ortholog); FOUND IN endomembrane system (inferred); glutamatergic synapse (inferred); membrane (inferred)				Pig	22	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
18483771	SORCS3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); regulation of long-term synaptic depression (ortholog); FOUND IN glutamatergic synapse (inferred); membrane (inferred); plasma membrane (inferred)				Green Monkey	19	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
625831963	Sorcs3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); positive regulation of synaptic transmission (ortholog); FOUND IN glutamatergic synapse (ortholog); plasma membrane (ortholog); postsynaptic density (ortholog)				Black Rat	14	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
18916382	Sorcs3	sortilin related VPS10 domain containing receptor 3	INVOLVED IN learning (ortholog); memory (ortholog); positive regulation of synaptic transmission (ortholog); FOUND IN glutamatergic synapse (ortholog); plasma membrane (ortholog); postsynaptic density membrane (ortholog)				Naked Mole-Rat	19	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
155249287	sorcs3.L						African Clawed Frog		symbol	gene, null
155252891	sorcs3.S						African Clawed Frog		symbol	gene, null
7241956	SORCS3-AS1	SORCS3 antisense RNA 1	INTERACTS WITH malathion	10	104664608	104666216	Human	1	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
5687731	Sorcs3^em1Mcwi	sortilin-related VPS10 domain containing receptor 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin	This allele was made by ZFN mutagenesis. The resulting mutation is a 33-bp insertion in exon 7 (del 1392-1419, ins. Gacgtggtagagcggtgcatcatgagttgtctctggatgcataggtacctgccacatcttgtaataacagcatggtactccgtcatgtgcatatatcttagctgcttcaaatgctccttaattccttgac)				Rat		symbol , old_gene_symbol	gene, allele
12713312	LOC101961565	VPS10 domain-containing receptor SorCS3	INVOLVED IN learning (ortholog); memory (ortholog); regulation of long-term synaptic depression (ortholog); FOUND IN glutamatergic synapse (inferred); membrane (inferred); plasma membrane (inferred)	NW_004936600	1040284	1610474	Squirrel	20	name , old_gene_symbol	gene, protein-coding, MODEL [RefSeq]