| 619753 | Smpd2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity; phosphoric diester hydrolase activity (ortholog); INVOLVED IN ceramide biosynthetic process; intracellular signal transduction; response to mechanical stimulus; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; sphingolipid metabolic pathway; FOUND IN caveola; plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 20 | 46568627 | 46571741 | Rat | 133 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 732430 | SMPD2 | sphingomyelin phosphodiesterase 2 | This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009] | 6 | 109440724 | 109443919 | Human | 132 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 732431 | Smpd2 | sphingomyelin phosphodiesterase 2, neutral | This gene encodes a protein with similarity to the human nSMase1 protein. In humans, the nSMase1 protein was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009] | 10 | 41363168 | 41366410 | Mouse | 141 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9026225 | Smpd2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits phosphoric diester hydrolase activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); ceramide metabolic process (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN tumor necr osis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | NW_004955411 | 34481431 | 34484423 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11729004 | SMPD2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | 6 | 107243751 | 107246941 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12405202 | SMPD2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | 12 | 66347628 | 66350322 | Dog | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12699572 | Smpd2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | NW_004936564 | 5565205 | 5568474 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14109363 | SMPD2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18911814 | Smpd2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits phosphoric diester hydrolase activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18708659 | SMPD2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular signal transduction (ortholog); response to mechanical stimulus (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237312 | smpd2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625886162 | Smpd2 | sphingomyelin phosphodiesterase 2 | ENCODES a protein that exhibits phosphoric diester hydrolase activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); ceramide metabolic process (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN tumor necr osis factor mediated signaling pathway; FOUND IN caveola (ortholog); plasma membrane (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |