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34 records found for search term Six6
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1310497Six6SIX homeobox 6ENCODES a protein that exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomalies with retinal and/or 69735788397375415Rat59symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1321431SIX6SIX homeobox 6The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with ca146050914660512850Human129symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1321432Six6sine oculis-related homeobox 6This gene encodes a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 12 and is thought to be involved in eye development. The encoded transcription factor regulates early progenitor cell proliferation during127298665672991673Mouse81symbol , old_gene_name , PhenoGengene, protein-coding, REVIEWED [RefSeq]
9020185Six6SIX homeobox 6ENCODES a protein that exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomalies with retinal and/or NW_00495546691202279122109Chinchilla9symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11883458SIX6SIX homeobox 6ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (inferred); regulation of transcription by RNA polym144111328241117018Bonobo20symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12253607SIX6SIX homeobox 6ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); sequence-specific double-stranded DNA binding (inferred); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomal83556583835568423Dog20symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12735358Six6SIX homeobox 6ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (inferred); regulation of transcription by RNA polymNW_00493649547163594719162Squirrel20symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14024916SIX6SIX homeobox 6ENCODES a protein that exhibits DNA binding (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); sequence-specific double-stranded DNA binding (inferred); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomalPig20symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18631919SIX6SIX homeobox 6ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (inferred); regulation of transcription by RNA polymGreen Monkey20symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18929007Six6SIX homeobox 6ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN eye development (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomalies wNaked Mole-Rat19symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155234430six6Tropical Clawed Frogsymbolgene, null
626118198Six6SIX homeobox 6ENCODES a protein that exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH Isolated Microphthalmia with Cataract 2 (ortholog); myopia (ortholog); optic disc anomalies with retinal and/or Black Rat9symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155243669six6.LAfrican Clawed Frogsymbolgene, null
155234429six6.SAfrican Clawed Frogsymbolgene, null
1559456Six6os1Six6 opposite strand transcript 1INVOLVED IN homologous chromosome pairing at meiosis (ortholog); meiotic cell cycle (ortholog); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (ortholog); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuff69731482997351069Rat46symbol , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
16207334930447C04RikRIKEN cDNA 4930447C04 geneInvolved in meiosis I; oogenesis; and spermatogenesis. Located in central element. Is expressed in several structures, including genitourinary system; intestine; liver; lung; and retina. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 18 and spermatogenic failure 52. Ortho127292696772964742Mouse74old_gene_name , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1350418C14orf39chromosome 14 open reading frame 39Involved in homologous chromosome pairing at meiosis. Predicted to be located in chromosome. Predicted to be active in central element. Implicated in primary ovarian insufficiency 18 and spermatogenic failure 52. [provided by Alliance of Genome Resources, Jul 2025]146043595660515544Human77old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
405855999six6os1Tropical Clawed Frogsymbolgene, null
405856816six6os1Tropical Clawed Frogsymbolgene, null
405857748six6os1Tropical Clawed Frogsymbolgene, null
405865553six6os1Tropical Clawed Frogsymbolgene, null
598152693six6os1Tropical Clawed Frogsymbolgene, null
405856000six6os1.SAfrican Clawed Frogsymbolgene, null
405859211six6os1.SAfrican Clawed Frogsymbolgene, null
405864205six6os1.SAfrican Clawed Frogsymbolgene, null
405865552six6os1.SAfrican Clawed Frogsymbolgene, null
626171025six6os1.SAfrican Clawed Frogsymbolgene, null
626182962six6os1p.LAfrican Clawed Frogsymbolgene, null
14210052C1H14orf39chromosome 1 C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (inferred); meiotic cell cycle (inferred); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (inferred); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuffPig22old_gene_namegene, protein-coding, MODEL [RefSeq]
18507019C24H14orf39chromosome 24 C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (inferred); meiotic cell cycle (inferred); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (inferred); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuffGreen Monkey22old_gene_namegene, protein-coding, MODEL [RefSeq]
626081958C7H14orf39chromosome 7 C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (ortholog); meiotic cell cycle (ortholog); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (ortholog); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuffBlack Rat18old_gene_namegene, protein-coding, MODEL [RefSeq]
12117408C8H14orf39chromosome 8 C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (inferred); meiotic cell cycle (inferred); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (inferred); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuff83548647635542214Dog22old_gene_namegene, protein-coding, MODEL [RefSeq]
18933181CUNH14orf39chromosome unknown C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (inferred); meiotic cell cycle (inferred); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (inferred); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuffNaked Mole-Rat22old_gene_namegene, protein-coding, MODEL [RefSeq]
11925840C15H14orf39chromosome 15 C14orf39 homologINVOLVED IN homologous chromosome pairing at meiosis (inferred); meiotic cell cycle (inferred); meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (inferred); ASSOCIATED WITH azoospermia (ortholog); primary ovarian insufficiency (ortholog); primary ovarian insuff144104031541090267Bonobo22old_gene_namegene, protein-coding, MODEL [RefSeq]