| 1310431 | Siae | sialic acid acetylesterase | ENCODES a protein that exhibits sialate O-acetylesterase activity (ortholog); INVOLVED IN carbohydrate metabolic process (ortholog); regulation of immune system process (ortholog); ASSOCIATED WITH autoimmune disease (ortholog); FOUND IN lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8- tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 45507465 | 45542740 | Rat | 110 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1332119 | Siae | sialic acid acetylesterase | Predicted to enable sialate O-acetylesterase activity. Predicted to be involved in carbohydrate metabolic process and regulation of immune system process. Located in lysosome. Is expressed in several structures, including abdominal fat pad; central nervous system; genitourinary system; immune system ; and yolk sac. Human ortholog(s) of this gene implicated in autoimmune disease. Orthologous to human SIAE (sialic acid acetylesterase). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 37525117 | 37559554 | Mouse | 132 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604014 | SIAE | sialic acid acetylesterase | This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011] | 11 | 124633113 | 124676303 | Human | 115 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8734297 | Siae | sialic acid acetylesterase | ENCODES a protein that exhibits sialate O-acetylesterase activity (ortholog); INVOLVED IN carbohydrate metabolic process (ortholog); regulation of immune system process (ortholog); ASSOCIATED WITH autoimmune disease (ortholog); FOUND IN lysosome (ortholog) | NW_004955412 | 25704024 | 25741646 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11903525 | SIAE | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); regulation of immune system process (inferred); ASSOCIATED WITH autoimmune disease (orth olog); FOUND IN lysosome (inferred) | 11 | 119463554 | 119503192 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12193785 | SIAE | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); regulation of immune system process (inferred); ASSOCIATED WITH autoimmune disease (orth olog); FOUND IN lysosome (inferred) | 5 | 9719444 | 9770574 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12556006 | Siae | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); regulation of immune system process (inferred); ASSOCIATED WITH autoimmune disease (orth olog); FOUND IN lysosome (inferred) | NW_004936743 | 1105461 | 1142028 | Squirrel | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14072665 | SIAE | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); regulation of immune system process (inferred); ASSOCIATED WITH autoimmune disease (orth olog); FOUND IN lysosome (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932320 | Siae | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN regulation of immune system process (ortholog); ASSOCIATED WITH autoimmune disease (ortholog); FOUND IN lysosome (inferred) | | | | Naked Mole-Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18618955 | SIAE | sialic acid acetylesterase | ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); hydrolase activity (inferred); sialate O-acetylesterase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); regulation of immune system process (inferred); ASSOCIATED WITH autoimmune disease (orth olog); FOUND IN lysosome (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626107164 | Siae | sialic acid acetylesterase | ENCODES a protein that exhibits sialate O-acetylesterase activity (ortholog); INVOLVED IN carbohydrate metabolic process (ortholog); regulation of immune system process (ortholog); ASSOCIATED WITH autoimmune disease (ortholog); FOUND IN lysosome (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253205 | siae | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155246639 | siae.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155251563 | siae.S | | | | | | African Clawed Frog | | symbol | gene, null |