| 1306440 | Sh3yl1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-t etrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 53250036 | 53293406 | Rat | 109 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315058 | SH3YL1 | SH3 and SYLF domain containing 1 | Enables phosphatase binding activity and phosphatidylinositol binding activity. Predicted to be involved in regulation of ruffle assembly. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in ruffle membrane. [provided by Alliance of Genome Resources, Jul 2025 ] | 2 | 218136 | 264824 | Human | 110 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1315059 | Sh3yl1 | Sh3 domain YSC-like 1 | Predicted to enable phosphatase binding activity and phosphatidylinositol binding activity. Acts upstream of or within phosphatidylinositol biosynthetic process and regulation of ruffle assembly. Predicted to be active in ruffle membrane. Orthologous to human SH3YL1 pan> (SH3 and SYLF domain containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 30961622 | 31010159 | Mouse | 119 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8856664 | Sh3yl1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (ortholog) | NW_004955487 | 258116 | 290377 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11926420 | SH3YL1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred) | 2A | 211952 | 257266 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12110299 | SH3YL1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred) | 17 | 202166 | 239508 | Dog | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12723629 | Sh3yl1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred) | NW_004936532 | 101571 | 127331 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247065 | sh3yl1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18927795 | Sh3yl1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14045293 | SH3YL1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 16 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625898336 | Sh3yl1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18667555 | SH3YL1 | SH3 and SYLF domain containing 1 | ENCODES a protein that exhibits phosphatase binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred) | | | | Green Monkey | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252331 | sh3yl1.L | | | | | | African Clawed Frog | | symbol | gene, null |