| 1307287 | Sh2d3c | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetr achlorodibenzodioxine | 3 | 36408305 | 36444191 | Rat | 80 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316391 | SH2D3C | SH2 domain containing 3C | This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding pr otein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] | 9 | 127738317 | 127778666 | Human | 84 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316392 | Sh2d3c | SH2 domain containing 3C | Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway and small GTPase-mediated signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in cytosol. Orthologous to human SH2D3C (SH2 domain containing 3C). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 32611072 | 32645008 | Mouse | 108 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8827671 | Sh2d3c | SH2 domain containing 3C | FOUND IN cytosol (ortholog) | NW_004955419 | 891133 | 921062 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11742531 | SH2D3C | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (inferred) | 9 | 98858018 | 98899661 | Bonobo | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12107632 | SH2D3C | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (inferred) | 9 | 55626379 | 55656667 | Dog | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12488472 | Sh2d3c | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (inferred) | NW_004936487 | 15410878 | 15440326 | Squirrel | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254204 | sh2d3c | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18932906 | Sh2d3c | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (ortholog) | | | | Naked Mole-Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18674334 | SH2D3C | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (inferred) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626149211 | Sh2d3c | SH2 domain containing 3C | FOUND IN cytosol (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14029415 | SH2D3C | SH2 domain containing 3C | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN small GTPase-mediated signal transduction (inferred); FOUND IN cytosol (inferred) | | | | Pig | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155260185 | sh2d3c.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252055 | sh2d3c.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16571323 | AL162586.2 | Novel transcript, antisense to SH2D3C | | | | | Human | | name | gene, lncrna |