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4 records found for search term Sgef
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1562559Arhgef26Rho guanine nucleotide exchange factor 26ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN endothelial cell morphogenesis (ortholog); ruffle assembly (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine2148889405149000538Rat132old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1603402ARHGEF26Rho guanine nucleotide exchange factor 26This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the enco3154121003154257825Human134old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1615422Arhgef26Rho guanine nucleotide exchange factor 26Acts upstream of or within endothelial cell morphogenesis and ruffle assembly. Is expressed in pons ventricular layer. Orthologous to human ARHGEF26 (Rho guanine nucleotide exchange factor 26). [provided by Alliance of Genome Resources, Jul 2025]36224494662369642Mouse136old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
12323689ARHGEF26Rho guanine nucleotide exchange factor 26ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN endothelial cell morphogenesis (ortholog); ruffle assembly (ortholog); FOUND IN cell projection (inferred); cytosol (inferred); plasma membrane (inferred)234829010548400879Dog12old_gene_symbolgene, protein-coding, MODEL [RefSeq]