| 1309451 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); COPII-coated vesicle cargo loading (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSO CIATED WITH progressive muscular atrophy (ortholog); FOUND IN COPII vesicle coat (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 36450043 | 36525303 | Rat | 105 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319800 | SEC24A | SEC24 homolog A, COPII component | The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory , plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] | 5 | 134648382 | 134727909 | Human | 120 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319801 | Sec24a | SEC24 homolog A, COPII coat complex component | Predicted to enable SNARE binding activity and zinc ion binding activity. Acts upstream of or within cholesterol homeostasis; positive regulation of protein secretion; and regulation of cholesterol transport. Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in embryo. Orthologous to human SEC24A (SEC24 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 51583090 | 51649172 | Mouse | 124 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8977769 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); COPII-coated vesicle cargo loading (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); ASSOCIATED WITH progressive muscular atrophy (ortholog); FOUND IN COPII ve sicle coat (ortholog) | NW_004955408 | 5803438 | 5850879 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11854849 | SEC24A | SEC24 homolog A, COPII component | ENCODES a protein that exhibits metal ion binding (inferred); SNARE binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH progressive muscul ar atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | 5 | 130050625 | 130128212 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12086803 | SEC24A | SEC24 homolog A, COPII coat complex component | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); progressive muscular atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | 11 | 22749633 | 22813045 | Dog | 35 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12552397 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits metal ion binding (inferred); SNARE binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH progressive muscul ar atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | NW_004936647 | 612640 | 689963 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866989 | SEC24A | SEC24 homolog A, COPII coat complex component | | | | | Green Monkey | | symbol | gene, protein-coding |
| 14167086 | SEC24A | SEC24 homolog A, COPII coat complex component | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); progressive muscular atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 31 | symbol , old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 18664112 | SEC24A | SEC24 homolog A, COPII component | ENCODES a protein that exhibits metal ion binding (inferred); SNARE binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH progressive muscul ar atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | | | | Green Monkey | 34 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625963283 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); COPII-coated vesicle cargo loading (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); ASSOCIATED WITH progressive muscular atrophy (ortholog); FOUND IN COPII ve sicle coat (ortholog) | | | | Black Rat | 13 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18918307 | Sec24a | SEC24 homolog A, COPII component | ENCODES a protein that exhibits metal ion binding (inferred); SNARE binding (inferred); zinc ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); positive regulation of protein secretion (ortholog); regulation of cholesterol transport (ortholog); ASSOCIATED WITH progressive muscul ar atrophy (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasmic vesicle (inferred); cytosol (inferred) | | | | Naked Mole-Rat | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155242568 | sec24a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155244266 | sec24a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255434 | sec24a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14387263 | Sec24AB | | | | | | Fly | | symbol | gene, null |
| 13442036 | SEC24AP1 | SEC24 homolog A pseudogene 1 | INTERACTS WITH okadaic acid | 17 | 69094100 | 69095506 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |