| 1309272 | Sall2 | spalt-like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 27494831 | 27512402 | Rat | 98 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319526 | Sall2 | spalt like transcription factor 2 | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within neural tube dev elopment. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; metanephros; neural ectoderm; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in coloboma. Orthologous to human SALL2 (spalt like transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 52548634 | 52566127 | Mouse | 113 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1345005 | SALL2 | spalt like transcription factor 2 | This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016] | 14 | 21521080 | 21537121 | Human | 112 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8966762 | Sall2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog) | NW_004955550 | 2236129 | 2250829 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11849721 | SALL2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | 14 | 2338806 | 2354970 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12379183 | SALL2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | 15 | 18558181 | 18571941 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12704125 | Sall2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | NW_004936880 | 670063 | 685532 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914132 | Sall2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18452218 | SALL2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626025834 | Sall2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14010793 | SALL2 | spalt like transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); nega tive regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coloboma (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233133 | sall2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155233134 | sall2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244836 | sall2.S | | | | | | African Clawed Frog | | symbol | gene, null |