| 3611 | Rxrb | retinoid X receptor beta | ENCODES a protein that exhibits nuclear receptor activity; nuclear retinoic acid receptor binding; nuclear thyroid hormone receptor binding; INVOLVED IN nuclear receptor-mediated signaling pathway; regulation of myelination; cardiac muscle cell proliferation (ortholog); PARTICIPATES IN retinoic acid signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; non-small cell lung carcinoma pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5-triiodo-L-thyronine | 20 | 4818707 | 4824968 | Rat | 204 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 11251 | Rxrb | retinoid X receptor beta | Enables chromatin DNA binding activity and transcription cis-regulatory region binding activity. Involved in cellular response to retinoic acid. Acts upstream of or within several processes, including cardiac muscle tissue development; maternal placenta development; and positive regulation of transc ription by RNA polymerase II. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; sensory organ; and urinary system. Orthologous to human RXRB (retinoid X receptor beta). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 34250786 | 34257377 | Mouse | 285 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 735628 | RXRB | retinoid X receptor beta | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcript ional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] | 6 | 33193588 | 33200853 | Human | 217 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8882384 | Rxrb | retinoid X receptor beta | ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); cellular response to retinoic acid (ortholog); in ute ro embryonic development (ortholog); PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955437 | 1767833 | 1774401 | Chinchilla | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11935621 | RXRB | retinoid X receptor beta | ENCODES a protein that exhibits identical protein binding (ortholog); nuclear receptor activity (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); in utero embryonic development (ortholog); maternal placenta development (ortholog) ; PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred) | 6 | 32765818 | 32772876 | Bonobo | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12361794 | RXRB | retinoid X receptor beta | ENCODES a protein that exhibits identical protein binding (ortholog); nuclear receptor activity (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); in utero embryonic development (ortholog); maternal placenta development (ortholog) ; PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred) | 12 | 2657058 | 2663648 | Dog | 66 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12531736 | Rxrb | retinoid X receptor beta | ENCODES a protein that exhibits identical protein binding (ortholog); nuclear receptor activity (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); in utero embryonic development (ortholog); maternal placenta development (ortholog) ; PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred) | NW_004936476 | 25655164 | 25662369 | Squirrel | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908108 | Rxrb | retinoid X receptor beta | ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); cellular response to retinoic acid (ortholog); in ute ro embryonic development (ortholog); PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18656546 | RXRB | retinoid X receptor beta | ENCODES a protein that exhibits identical protein binding (ortholog); nuclear receptor activity (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); in utero embryonic development (ortholog); maternal placenta development (ortholog) ; PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246619 | rxrb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13897289 | RXRB | retinoid X receptor beta | ENCODES a protein that exhibits identical protein binding (ortholog); nuclear receptor activity (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); in utero embryonic development (ortholog); maternal placenta development (ortholog) ; PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleoplasm (inferred); INTERACTS WITH etoxazole | | | | Pig | 66 | symbol , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626124782 | Rxrb | retinoid X receptor beta | ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); cellular response to retinoic acid (ortholog); in ute ro embryonic development (ortholog); PARTICIPATES IN retinoic acid signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242004 | rxrb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246618 | rxrb.S | | | | | | African Clawed Frog | | symbol | gene, null |