| 1309449 | Rxfp2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding; protein-hormone receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of apoptotic process; negative regulation of cell population proliferation; ASSOCIATED WIT H cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 12 | 9961175 | 10023098 | Rat | 55 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319797 | RXFP2 | relaxin family peptide receptor 2 | This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] | 13 | 31739526 | 31803389 | Human | 68 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319798 | Rxfp2 | relaxin/insulin-like family peptide receptor 2 | Enables protein-hormone receptor activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway and male gonad development. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; genitourinary system; and perito neum. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human RXFP2 (relaxin family peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 149941487 | 150006015 | Mouse | 102 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8856231 | Rxfp2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); protein-hormone receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ma le gonad development (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955431 | 14050537 | 14105852 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11731328 | RXFP2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); male gonad development (ortholog); ASSOCIATED WI TH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | 13 | 12998696 | 13062548 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12277651 | RXFP2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); male gonad development (ortholog); ASSOCIATED WI TH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | 25 | 8307850 | 8368438 | Dog | 25 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12619280 | Rxfp2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); male gonad development (ortholog); ASSOCIATED WI TH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | NW_004936472 | 26425829 | 26487700 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242962 | rxfp2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625870443 | Rxfp2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); protein-hormone receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ma le gonad development (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14218065 | RXFP2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); male gonad development (ortholog); ASSOCIATED WI TH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane; INTERACTS WITH zearalenone | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 15039277 | RXFP2 | relaxin/insulin-like family peptide receptor 2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protein-hormone receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 11 | symbol | gene, protein-coding |
| 18517306 | RXFP2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); male gonad development (ortholog); ASSOCIATED WI TH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18904684 | Rxfp2 | relaxin family peptide receptor 2 | ENCODES a protein that exhibits peptide hormone binding (ortholog); protein-hormone receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); ma le gonad development (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); disorder of sexual development (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242476 | rxfp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252543 | rxfp2.S | | | | | | African Clawed Frog | | symbol | gene, null |