| 621398 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (ortholog); INVOLVED IN regulation of angiogenesis (ortholog); tRNA stabilization (ortholog); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (ortholog); cytoplasm (ortholog); cyto sol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 1 | 205698882 | 205711348 | Rat | 141 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 735371 | RNH1 | ribonuclease/angiogenin inhibitor 1 | Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhib itor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010] | 11 | 494515 | 507242 | Human | 156 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 735372 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | Predicted to enable ribonuclease inhibitor activity. Predicted to be involved in cell migration; regulation of Arp2/3 complex-mediated actin nucleation; and regulation of angiogenesis. Predicted to be located in cytosol. Predicted to be part of angiogenin-PRI complex. Predicted to be active in sever al cellular components, including lamellipodium; nucleoplasm; and plasma membrane. Is expressed in bladder; blood; embryo; pancreas; and yolk sac. Orthologous to human RNH1 (ribonuclease/angiogenin inhibitor 1). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 140740239 | 140752764 | Mouse | 157 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8893272 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (ortholog); INVOLVED IN regulation of angiogenesis (ortholog); tRNA stabilization (ortholog); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (ortholog); cytoplasm (ortholog); cyto sol (ortholog) | NW_004955476 | 11543006 | 11549391 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11927417 | RNH1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (inferred); INVOLVED IN regulation of angiogenesis (inferred); tRNA stabilization (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (inferred); cytoplasm (inferred); cyto sol (inferred) | 11 | 502203 | 514342 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12058719 | RNH1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (inferred); INVOLVED IN regulation of angiogenesis (inferred); tRNA stabilization (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (inferred); cytoplasm (inferred); cyto sol (inferred) | 18 | 25604736 | 25614602 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12513003 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (inferred); INVOLVED IN regulation of angiogenesis (inferred); tRNA stabilization (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (inferred); cytoplasm (inferred); cyto sol (inferred) | NW_004936888 | 352493 | 362501 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14384756 | RNH1 | | | | | | Yeast | | symbol | gene, null |
| 14384759 | rnh1 | | | | | | Fly | | symbol | gene, null |
| 18595460 | RNH1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (inferred); INVOLVED IN regulation of angiogenesis (inferred); tRNA stabilization (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (inferred); cytoplasm (inferred); cyto sol (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625956308 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (ortholog); INVOLVED IN regulation of angiogenesis (ortholog); tRNA stabilization (ortholog); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN angiogenin-PRI complex (ortholog); cytoplasm (ortholog); cyto sol (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13995779 | RNH1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity; INVOLVED IN regulation of angiogenesis (inferred); tRNA stabilization (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholog); FOUND IN cytoplasm; nucleus (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919007 | Rnh1 | ribonuclease/angiogenin inhibitor 1 | ENCODES a protein that exhibits ribonuclease inhibitor activity (inferred); INVOLVED IN positive regulation of inflammatory response (inferred); regulation of angiogenesis (inferred); regulation of inflammatory response (inferred); ASSOCIATED WITH ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, 3 (ortholo g); FOUND IN angiogenin-PRI complex (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1319116 | RNASEH1 | ribonuclease H1 | This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The productio n of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017] | 2 | 3531813 | 3558333 | Human | 167 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1604714 | RNASEH1P1 | ribonuclease H1 pseudogene 1 | | 17 | 20901955 | 20902777 | Human | | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
