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28 records found for search term Rnf6
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1306092Rnf6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); nuclear androgen receptor binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K27-linked ubiquiti121392916013940663Rat122symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1314509RNF6ring finger protein 6The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in th132613211526223085Human135symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1550389Rnf6ring finger protein (C3H2C3 type) 6Enables DNA binding activity and ubiquitin protein ligase activity. Involved in protein K48-linked ubiquitination and ubiquitin-dependent protein catabolic process. Acts upstream of or within negative regulation of axon extension and positive regulation of DNA-templated transcription. Located in PML5146146003146158267Mouse140symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8785435Rnf6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); nuclear androgen receptor binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K27-linked ubiquitiNW_00495549757444855754728Chinchilla29symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11682152RNF6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Esophageal Neoplasms (ortholog); esophagus squamous cell 1375056697515542Bonobo36symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12187130RNF6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Esophageal Neoplasms (ortholog); esophagus squamous cell 251319920113240347Dog36symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12617299Rnf6ring finger protein 6ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); nuclear androgen receptor binding (inferred); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); ubiquitin-dependent protein catabolic proceNW_0049369485780667875Squirrel37symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18929067Rnf6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); nuclear androgen receptor binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K27-linked ubiNaked Mole-Rat35symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
625992398Rnf6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); nuclear androgen receptor binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K27-linked ubiquitiBlack Rat29symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14116325RNF6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Esophageal Neoplasms (ortholog); esophagus squamous cell Pig36symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18755615RNF6ring finger protein 6ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN negative regulation of axon extension (ortholog); positive regulation of DNA-templated transcription (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Esophageal Neoplasms (ortholog); esophagus squamous cell Green Monkey36symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11720958LOC100985144E3 ubiquitin-protein ligase RNF6-like132182611521828984Bonobonamegene, pseudo, MODEL [RefSeq]
18925994LOC101706014E3 ubiquitin-protein ligase RNF6-likeNaked Mole-Ratnamegene, pseudo, MODEL [RefSeq]
18633900LOC103214321E3 ubiquitin-protein ligase RNF6-likeGreen Monkeynamegene, pseudo, MODEL [RefSeq]
8743364LOC102029029E3 ubiquitin-protein ligase RNF6 pseudogeneNW_0049554023465794434659539Chinchillaold_gene_name , namegene, pseudo, MODEL [RefSeq]
5131388RNF6P1ring finger protein 6 pseudogene 1213937376339374421Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1602493MID2midline 2The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gX107825735107931637Human99old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1347564MKRN1makorin ring finger protein 1This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thoug7140453033140479569Human81old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1321625MKRN2makorin ring finger protein 2This gene encodes a probable E3 ubiquitin ligase containing several zinc finger domains, that is a member of the makorin RING zinc-finger protein family. This gene overlaps the v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1) gene in an antisense orientation and may have a co-regulatory funct31255708712583713Human88old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1322529MKRN3makorin ring finger protein 3The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of152356567423568044Human171old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1350230MKRN4Pmakorin ring finger protein 4, pseudogenePredicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Jul 2025]X4083425440837807Human13old_gene_symbolgene, pseudo, INFERRED [RefSeq]
1349030MKRN9Pmakorin ring finger protein 9, pseudogeneINTERACTS WITH tebuconazole128778288587784711Human1old_gene_symbolgene, pseudo, VALIDATED [RefSeq]
733503MNAT1MNAT1 component of CDK activating kinaseThe protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding differe146073476160969965Human107old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315966NEURL1neuralized E3 ubiquitin protein ligase 1Predicted to enable translation factor activity, non-nucleic acid binding and ubiquitin protein ligase activity. Involved in negative regulation of Notch signaling pathway; negative regulation of cell population proliferation; and positive regulation of apoptotic process. Located in plasma membrane.10103493705103592546Human134old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1557823Neurl1aneuralized E3 ubiquitin protein ligase 1AEnables translation factor activity, non-nucleic acid binding and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of filopodium assembly; positive regulation of long-term neuronal synaptic plasticity; and regulation of synapse organization. Acts upstre194716725947247880Mouse144old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1349943PCGF1polycomb group ring finger 1PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]27450504374507695Human89old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1319563PEX10peroxisomal biogenesis factor 10This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger sy124039742413827Human339old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
2303667NEURL1Bneuralized E3 ubiquitin protein ligase 1BPredicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent endocytosis. Located in actin cytoskeleton and cytosol. [provided by Alliance of Genome Resources, Jul 2025]5172641263172691540Human108old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]