RGD:12345 Gene Search Result

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8 records found for search term 12345

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
5147014	Gm12345	predicted gene 12345		11	77040339	77041548	Mouse		symbol , PhenoGen , name	gene, pseudo, INFERRED [RefSeq]
1344662	AMOT	angiomotin	This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate th ... (more) e inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]	X	112774877	112840831	Human	176	PubMed	gene, protein-coding, REVIEWED [RefSeq]
1549975	Capzb	capping actin protein of muscle Z-line subunit beta	This gene encodes the beta subunit of a highly conserved filamentous actin capping protein that binds the barbed end of filamentous actin to stabilize it and terminate elongation. Interaction of this protein with the barbed end of the actin filament occurs through binding of the amphipathic helix at ... (more) the C-terminus to the hydrophobic cleft on the actin molecule. This gene is required for a variety of dynamic actin-mediated processes including organization of lamellipodia and filopodia, growth cone morphology and neurite outgrowth in hippocampal neurons, and asymmetric spindle migration and polar body extrusion during oocyte maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]	4	138920210	139019131	Mouse	172	NCBI Gene , KEGG Report	gene, protein-coding, REVIEWED [RefSeq]
1315832	POLR2C	RNA polymerase II subunit C	This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core suba ... (more) ssembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]	16	57462679	57472009	Human	96	PubMed	gene, protein-coding, REVIEWED [RefSeq]
737096	TNFSF15	TNF superfamily member 15	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ... (more) ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]	9	114784635	114806039	Human	168	PubMed	gene, protein-coding, REVIEWED [RefSeq]
1347212	TRR-TCG4-1	tRNA-Arg (anticodon TCG) 4-1		6	26299677	26299749	Human		HGNC ID	gene, trna, MODEL [RefSeq]
12308038	LMCD1	LIM and cysteine rich domains 1	ENCODES a protein that exhibits metal ion binding (inferred); transcription corepressor activity (inferred); zinc ion binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH coronary stenosis (ortholog); mitral valve insufficiency (orthol ... (more) og); mitral valve prolapse (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)	20	9524393	9582939	Dog	23	array_id_affy_canine_2_ensembl	gene, protein-coding, MODEL [RefSeq]
12107454	GLYAT	glycine-N-acyltransferase	ENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to toxic substance (inferred); FO ... (more) UND IN mitochondrion (inferred)	18	37689076	37715614	Dog	21	array_id_affy_canine_2_ensembl	gene, protein-coding, MODEL [RefSeq]