| 61842 | Psma2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH heart disease (ortholo g); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); P-body (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 55250054 | 55260441 | Rat | 165 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 62134 | Psma2 | proteasome subunit alpha 2 | Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in P-body. Part of proteasome core complex. Orthologous to human PSMA2 (proteasome 20S subunit alpha 2). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 14787827 | 14800258 | Mouse | 178 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 732886 | PSMA2 | proteasome 20S subunit alpha 2 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throug hout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008] | 7 | 42916861 | 42932174 | Human | 212 | symbol , COSMIC , ensembl_full_name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9055703 | Psma2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog) ; nucleus (ortholog); P-body (ortholog) | NW_004955460 | 880795 | 890718 | Chinchilla | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11830889 | PSMA2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN P-body (ortholog) | 7 | 41304746 | 41319844 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12279722 | PSMA2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); response to oxidative stress (ortholog); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); P-body (ortholo g) | 18 | 7218150 | 7228859 | Dog | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12723971 | Psma2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog) ; nucleus (ortholog); P-body (ortholog) | NW_004936478 | 18083525 | 18095088 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18917225 | Psma2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog) ; nucleus (ortholog); P-body (ortholog) | | | | Naked Mole-Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18631508 | PSMA2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); P-body (inferred) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626068301 | Psma2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (ortholog) ; nucleus (ortholog); P-body (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14118533 | PSMA2 | proteasome 20S subunit alpha 2 | INVOLVED IN proteasomal protein catabolic process (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH heart disease (ortholog); osteoporosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241573 | psma2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155252853 | psma2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248034 | psma2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2323949 | Psma2-ps1 | proteasome 20S subunit alpha 2, pseudogene 1 | | 4 | 28792322 | 28793014 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1597239 | Psma2-ps2 | proteasome 20S subunit alpha 2, pseudogene 2 | | X | 7914041 | 7914733 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 6482614 | PSMA2P1 | proteasome subunit alpha 2 pseudogene 1 | | 11 | 87329214 | 87330058 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6482613 | PSMA2P2 | proteasome subunit alpha 2 pseudogene 2 | | 8 | 93940086 | 93942877 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6482917 | PSMA2P3 | proteasome subunit alpha 2 pseudogene 3 | | 2 | 202179344 | 202179986 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |