| 620964 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding; protein kinase activity; protein kinase C binding; INVOLVED IN cellular response to angiotensin; cellular response to endothelin; cellular response to norepinephrine stimulus; PARTICIPATES IN insulin-like growth factor signaling pathway; AS SOCIATED WITH Cardiomegaly; myocardial infarction; adenocarcinoma (ortholog); FOUND IN cytoplasm; membrane; nucleus; INTERACTS WITH (R)-noradrenaline; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 73460640 | 73774433 | Rat | 325 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1351212 | PRKD1 | protein kinase D1 | The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulatio n of cell shape and adhesion. [provided by RefSeq, Jan 2017] | 14 | 29576479 | 29927847 | Human | 357 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551913 | Prkd1 | protein kinase D1 | Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of NLRP3 inflammasome complex assembly; positive regulation of osteoblast differentiation; and positive regulation of protein import into nucleus. Acts upstream of or within regulation of r elease of sequestered calcium ion into cytosol. Located in several cellular components, including cell cortex; cell-cell junction; and trans-Golgi network. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to human PRKD1 (protein kinase D1). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 50388009 | 50696075 | Mouse | 357 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9016154 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits diacylglycerol-dependent serine/threonine kinase activity (ortholog); heat shock protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN autophagosome membrane (ortholog); cell cortex (ortholog); cell-cell junction (ortholog) | NW_004955409 | 30554095 | 30860588 | Chinchilla | 110 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11744470 | PRKD1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); protein kinase activity (ortholog); protein kinase C binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); cellular response to norepinephrine stimulus (ortholog) ; PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); nucleus (ortholog) | 14 | 10353284 | 10707841 | Bonobo | 121 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12359120 | PRKD1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); protein kinase activity (ortholog); protein kinase C binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); cellular response to norepinephrine stimulus (ortholog) ; PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); nucleus (ortholog) | 8 | 9004641 | 9327054 | Dog | 118 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12554491 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); protein kinase activity (ortholog); protein kinase C binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); cellular response to norepinephrine stimulus (ortholog) ; PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); nucleus (ortholog) | NW_004936494 | 4469092 | 4601183 | Squirrel | 120 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914588 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); identical protein binding (ortholog); phosphatidylinositol 3-kinase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN autophagosome membrane (ortholog); cell cortex (ortholog); cell-cell junction (ortholog) | | | | Naked Mole-Rat | 122 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625882048 | Prkd1 | protein kinase D1 | ENCODES a protein that exhibits diacylglycerol-dependent serine/threonine kinase activity (ortholog); heat shock protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN autophagosome membrane (ortholog); cell cortex (ortholog); cell-cell junction (ortholog) | | | | Black Rat | 109 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14235793 | PRKD1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); protein kinase activity (ortholog); protein kinase C binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); cellular response to norepinephrine stimulus (ortholog) ; PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); nucleus (ortholog) | | | | Pig | 118 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 15039278 | PRKD1 | protein kinase D1 | | | | | Pig | | symbol | gene, protein-coding |
| 598133782 | PRKD1 | protein kinase D1 | ENCODES a protein that exhibits heat shock protein binding (ortholog); protein kinase activity (ortholog); protein kinase C binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to endothelin (ortholog); cellular response to norepinephrine stimulus (ortholog) ; PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Cardiac Fibrosis (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); nucleus (ortholog) | | | | Green Monkey | 121 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256954 | prkd1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155252182 | prkd1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241936 | prkd1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16561472 | AL133372.3 | novel transcript, antisense to PRKD1 | | | | | Human | | name | gene, lncrna |
| 16572236 | AL355053.1 | novel transcript, antisense to PRKD1 | | | | | Human | | name | gene, lncrna |
| 16561206 | AL356756.1 | novel transcript, antisense to PRKD1 | | | | | Human | | name | gene, lncrna |