Ppm1k Gene Search Result

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15 records found for search term Ppm1k

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1308501	Ppm1k	protein phosphatase, Mg2+/Mn2+ dependent, 1K	ENCODES a protein that exhibits manganese ion binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH ... (more) congestive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine	4	88942226	88969139	Rat	137	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1353112	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent 1K	This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, ... (more) Sep 2012]	4	88257620	88284561	Human	154	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1552216	Ppm1k	protein phosphatase 1K (PP2C domain containing)	Predicted to enable manganese ion binding activity and protein serine/threonine phosphatase activity. Involved in regulation of mitochondrial membrane permeability involved in apoptotic process. Located in mitochondrial matrix. Is expressed in several structures, including diaphragm; gut; liver; lun ... (more) g; and spleen. Used to study maple syrup urine disease. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K). [provided by Alliance of Genome Resources, Jul 2025]	6	57483487	57512537	Mouse	148	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8976471	Ppm1k	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits manganese ion binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH ... (more) congestive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)	NW_004955474	12229658	12250783	Chinchilla	15	symbol	gene, protein-coding, MODEL [RefSeq]
12043966	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH conge ... (more) stive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)	4	80548652	80575555	Bonobo	22	symbol	gene, protein-coding, MODEL [RefSeq]
12069352	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH conge ... (more) stive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)	32	11599758	11624777	Dog	25	symbol	gene, protein-coding, MODEL [RefSeq]
12482653	Ppm1k	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN branched-chain amino acid catabolic process (inferred); regulation of mitochondrial membrane permeability involve ... (more) d in apoptotic process (inferred); ASSOCIATED WITH congestive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)	NW_004936685	742081	765728	Squirrel	23	symbol	gene, protein-coding, MODEL [RefSeq]
14078227	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH conge ... (more) stive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred); INTERACTS WITH deoxynivalenol				Pig	26	symbol	gene, protein-coding, MODEL [RefSeq]
18916268	Ppm1k	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits manganese ion binding (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); ASSOCIATED WITH congestive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondria ... (more) l matrix (inferred); mitochondrion (inferred)				Naked Mole-Rat	21	symbol	gene, protein-coding, MODEL [RefSeq]
18677265	PPM1K	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity (inferred); cation binding (inferred); hydrolase activity (inferred); INVOLVED IN regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH conge ... (more) stive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)				Green Monkey	22	symbol	gene, protein-coding, MODEL [RefSeq]
155236588	ppm1k						Tropical Clawed Frog		symbol	gene, null
625899778	Ppm1k	protein phosphatase, Mg2+/Mn2+ dependent 1K	ENCODES a protein that exhibits manganese ion binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); regulation of mitochondrial membrane permeability involved in apoptotic process (ortholog); ASSOCIATED WITH ... (more) congestive heart failure (ortholog); maple syrup urine disease (ortholog); mild variant of maple syrup urine disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)				Black Rat	14	symbol	gene, protein-coding, MODEL [RefSeq]
155239945	ppm1k.L						African Clawed Frog		symbol	gene, null
155256030	ppm1k.S						African Clawed Frog		symbol	gene, null
13825076	PPM1K-DT	PPM1K divergent transcript		4	88284930	88341657	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]