| 1349201 | POLR2L | RNA polymerase II, I and III subunit L | This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the ot her two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008] | 11 | 839721 | 842529 | Human | 116 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1566209 | Polr2l | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase II (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase I I transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA polymerase I complex (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; bisphenol A | 1 | 205999607 | 206001615 | Rat | 102 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1623217 | Polr2l | polymerase (RNA) II (DNA directed) polypeptide L | Predicted to enable zinc ion binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Pre dicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and respiratory system. Orthologous to human POLR2L (RNA polymerase II, I and III subunit L). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 141051773 | 141055066 | Mouse | 121 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 10256792 | Polr2l | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase II (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase I I transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA polymerase I complex (ortholog) | NW_004955476 | 11291215 | 11293536 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12558433 | Polr2l | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); zinc ion binding (inferred); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); transcription elongation by RNA polymerase I ( ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004936544 | 652968 | 653683 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13385227 | POLR2L | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits chitin binding (inferred); DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); DNA-templated transcription (inferred); termination of RNA polymerase III transcription (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription pathway; RNA polymerase III transcription pathway; FOUND IN DNA-directed RNA polymerase complex (inferred); extracellular region (inferred); lysosome (inferred); INTERACTS WITH bisphenol A | 18 | 45201194 | 45203825 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 32727251 | POLR2L | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase II (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase I I transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA polymerase I complex (ortholog) | 11 | 859015 | 861382 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18444670 | POLR2L | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); metal ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); termination of RNA polymerase III transcription (inferred); transcription by RNA polymerase I (inferred); PARTICI PATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription pathway; RNA polymerase III transcription pathway; FOUND IN DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14068181 | POLR2L | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); metal ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); FOUND IN DNA-directed RNA polymerase complex (inferred); nucleus (inferred); RNA polymerase II, core complex (inf erred) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18911187 | Polr2l | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); metal ion binding (inferred); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); transcription elongation by RNA polymerase I (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626082367 | Polr2l | RNA polymerase II, I and III subunit L | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase II (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase I I transcription pathway; RNA polymerase III transcription pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA polymerase I complex (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250312 | polr2l.1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155255664 | polr2l.2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 1564685 | Polr2l-ps1 | RNA polymerase II, I and III subunit L, pseudogene 1 | | 19 | 8341713 | 8342080 | Rat | | symbol , PhenoGen , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1597729 | Polr2l-ps2 | RNA polymerase II, I and III subunit L, pseudogene 2 | | 4 | 153097856 | 153098234 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 7610492 | Polr2l-ps3 | RNA polymerase II, I and III subunit L, pseudogene 3 | | 10 | 87196508 | 87197846 | Rat | | symbol , PhenoGen , old_gene_symbol | gene, pseudo, MODEL [RefSeq] |
| 155250313 | polr2l.1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155237683 | polr2l.1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 628359618 | polr2l.2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 13558085 | LOC112440089 | RNA polymerase II, I and III subunit L | | 6 | 30886703 | 30887284 | Bonobo | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1345066 | POLR2LP1 | RNA polymerase II subunit L pseudogene 1 | | 6 | 31140727 | 31140913 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |