| 1308658 | Pla2g4b | phospholipase A2 group IVB | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN glycerophospholipid catabolic process (ortholog); phosphatidylcholine acyl-chain remodeling (ortholog); ph osphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytosol (ortholog); early endosome membrane (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1 | 3 | 127458022 | 127467637 | Rat | 109 | symbol , PhenoGen | gene, protein-coding, INFERRED [RefSeq] |
| 1318557 | PLA2G4B | phospholipase A2 group IVB | This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through tra nscripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains. [provided by RefSeq, Jul 2008] | 15 | 41838847 | 41848143 | Human | 115 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1318558 | Pla2g4b | phospholipase A2, group IVB (cytosolic) | Enables lysophospholipase activity and phospholipase A2 activity. Predicted to be involved in glycerophospholipid catabolic process. Predicted to be located in early endosome membrane and mitochondrial inner membrane. Predicted to be active in cytosol. Is expressed in several structures, including a limentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to several human genes including PLA2G4B (phospholipase A2 group IVB). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 119863914 | 119873514 | Mouse | 60 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8897228 | Pla2g4b | phospholipase A2 group IVB | ENCODES a protein that exhibits calcium-dependent phospholipase A2 activity (ortholog); phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN glycerophospholipid catabolic process (ortholog); phosphatidylcholine acyl-chain remodeling (ortholo g); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytosol (ortholog); early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | NW_004955416 | 8633249 | 8643219 | Chinchilla | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12120165 | PLA2G4B | phospholipase A2 group IVB | ENCODES a protein that exhibits phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharma codynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | 30 | 8865941 | 8878687 | Dog | 68 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12672376 | Pla2g4b | phospholipase A2 group IVB | ENCODES a protein that exhibits phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharma codynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | NW_004936471 | 5145736 | 5153930 | Squirrel | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18561592 | PLA2G4B | phospholipase A2 group IVB | ENCODES a protein that exhibits calcium-dependent phospholipase A2 activity (ortholog); phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN glycerophospholipid catabolic process (ortholog); phosphatidylcholine acyl-chain remodeling (ortholo g); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytosol (ortholog); early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | | | | Green Monkey | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922926 | Pla2g4b | phospholipase A2 group IVB | ENCODES a protein that exhibits phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharma codynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | | | | Naked Mole-Rat | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 153286793 | PLA2G4B | phospholipase A2 group IVB | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); glycerophospholipid metabolic process (inferred); lipid catabolic process (inferred); FOUND IN cytosol (inferred); membrane (inferred) | | | | Green Monkey | 23 | symbol | gene, protein-coding |
| 13890690 | PLA2G4B | phospholipase A2 group IVB | ENCODES a protein that exhibits phosphatidylcholine lysophospholipase A1 activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharma codynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog) | | | | Pig | 68 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2290030 | JMJD7-PLA2G4B | JMJD7-PLA2G4B readthrough | This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequ ence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013] | 15 | 41828092 | 41848143 | Human | 69 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 155231412 | jmjd7-pla2g4b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155237815 | jmjd7-pla2g4b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 9679283 | Gm28042 | predicted gene, 28042 | This locus represents naturally-occurring readthrough transcription between the neighboring Jmjd7 (jumonji domain containing 7) and Pla2g4b (phospholipase A2, group IVB (cytosolic)) genes on chromosome 2. The readthrough transcript is a candidate for nonsense-me diated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Oct 2013] | 2 | 119857964 | 119873514 | Mouse | | description , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |