| 1352736 | PKD1L1 | polycystin 1 like 1, transient receptor potential channel interacting | This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have b een described but their biological nature has not been determined. [provided by RefSeq, Jul 2008] | 7 | 47774614 | 47960906 | Human | 120 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1564724 | Pkd1l1 | polycystin 1 like 1, transient receptor potential channel interacting | ENCODES a protein that exhibits calcium channel activity (inferred); INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (orthol og); FOUND IN calcium channel complex (ortholog); ciliary membrane (ortholog); cilium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 14 | 87766745 | 87888647 | Rat | 63 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1615749 | Pkd1l1 | polycystic kidney disease 1 like 1 | Predicted to enable calcium channel activity. Involved in detection of nodal flow and left/right axis specification. Acts upstream of or within determination of left/right symmetry and heart development. Located in cilium. Is expressed in cochlea; node; and notochord. Human ortholog(s) of this gene implicated in visceral heterotaxy 8. Orthologous to human PKD1L1 (polycystin 1 like 1, transient receptor potential channel interacting). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 8782025 | 8924365 | Mouse | 77 | symbol , PhenoGen , description | gene, protein-coding, MODEL [RefSeq] |
| 9004493 | Pkd1l1 | polycystin 1 like 1, transient receptor potential channel interacting | INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN calcium channel complex (ortholog); ciliary membrane (o rtholog); cilium (ortholog) | NW_004955456 | 5497126 | 5582342 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11960971 | PKD1L1 | polycystin 1 like 1, transient receptor potential channel interacting | ENCODES a protein that exhibits calcium channel activity (inferred); monoatomic cation channel activity (inferred); INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN cilium (ortholog) | 7 | 48451329 | 48596991 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12338685 | PKD1L1 | polycystin 1 like 1, transient receptor potential channel interacting | ENCODES a protein that exhibits calcium channel activity (inferred); INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (orthol og); FOUND IN calcium channel complex (inferred); ciliary membrane (inferred); cilium (inferred) | 16 | 119639 | 199418 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12574037 | Pkd1l1 | polycystin 1 like 1, transient receptor potential channel interacting | ENCODES a protein that exhibits calcium channel activity (inferred); monoatomic cation channel activity (inferred); INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN calcium channel complex (ortholog); non-motile cilium (ortholog) | NW_004936478 | 22255887 | 22389477 | Squirrel | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18511071 | PKD1L1 | polycystin 1 like 1, transient receptor potential channel interacting | INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN calcium channel complex (ortholog); ciliary membrane (o rtholog); cilium (ortholog) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18917638 | Pkd1l1 | polycystin 1 like 1, transient receptor potential channel interacting | ENCODES a protein that exhibits calcium channel activity (inferred); monoatomic cation channel activity (inferred); INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN calcium channel complex (ortholog); non-motile cilium (ortholog) | | | | Naked Mole-Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625924273 | Pkd1l1 | polycystin 1 like 1, transient receptor potential channel interacting | INVOLVED IN detection of nodal flow (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital chylothorax (ortholog); genetic disease (ortholog); FOUND IN calcium channel complex (ortholog); ciliary membrane (o rtholog); cilium (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284194328 | pkd1l1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 286068208 | pkd1l1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1605032 | PKD1L1-AS1 | PKD1L1 antisense RNA 1 | Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 47795291 | 47819847 | Human | 5 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |