Pik3r5 Gene Search Result

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16 records found for search term Pik3r5

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1346928	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5	Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, ... (more) and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]	17	8878916	8965707	Human	213	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1563261	Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity; G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol metabolic process; G protein-coupled receptor signaling pathway (ortholog); phosphatidylinositol 3-kinase/protein kinase B sig ... (more) nal transduction (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN phosphatidylinositol 3-kinase complex; centriolar satellite (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol	10	53631469	53699550	Rat	174	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1620477	Pik3r5	phosphoinositide-3-kinase regulatory subunit 5	Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity and G-protein beta/gamma-subunit complex binding activity. Predicted to be involved in several processes, including phosphatidylinositol 3-kinase/protein kinase B signal transduction; phosphatidylinositol metabolic process; and p ... (more) ositive regulation of intracellular signal transduction. Predicted to be located in centriolar satellite; cytosol; and membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA and phosphatidylinositol 3-kinase complex, class IB. Is expressed in brain and retina nuclear layer. Human ortholog(s) of this gene implicated in ataxia with oculomotor apraxia type 3 and colon cancer. Orthologous to human PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5). [provided by Alliance of Genome Resources, Jul 2025]	11	68322951	68388675	Mouse	180	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8908983	Pik3r5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); ... (more) phosphatidylinositol metabolic process (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN centriolar satellite (ortholog); cytoplasm (ortholog); cytosol (ortholog)	NW_004955467	8025231	8091406	Chinchilla	24	symbol	gene, protein-coding, MODEL [RefSeq]
12034823	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol metabolic process (ortholog); positi ... (more) ve regulation of MAP kinase activity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN membrane (ortholog); phosphatidylinositol 3-kinase complex (ortholog)	17	42686483	42773668	Bonobo	27	symbol	gene, protein-coding, MODEL [RefSeq]
12316334	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol metabolic process (ortholog); positi ... (more) ve regulation of MAP kinase activity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN membrane (ortholog); phosphatidylinositol 3-kinase complex (ortholog)	5	33538354	33604984	Dog	27	symbol	gene, protein-coding, MODEL [RefSeq]
12681432	Pik3r5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol metabolic process (ortholog); positi ... (more) ve regulation of MAP kinase activity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN membrane (ortholog); phosphatidylinositol 3-kinase complex (ortholog)	NW_004936595	2029074	2053954	Squirrel	27	symbol	gene, protein-coding, MODEL [RefSeq]
625868877	Pik3r5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); ... (more) phosphatidylinositol metabolic process (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN centriolar satellite (ortholog); cytoplasm (ortholog); cytosol (ortholog)				Black Rat	24	symbol	gene, protein-coding, MODEL [RefSeq]
18433519	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol metabolic process (ortholog); positi ... (more) ve regulation of MAP kinase activity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN membrane (ortholog); phosphatidylinositol 3-kinase complex (ortholog)				Green Monkey	27	symbol	gene, protein-coding, MODEL [RefSeq]
155236487	pik3r5						Tropical Clawed Frog		symbol	gene, null
18933673	Pik3r5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol metabolic process (ortholog); positi ... (more) ve regulation of MAP kinase activity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN centriolar satellite (ortholog); cytosol (ortholog); membrane (ortholog)				Naked Mole-Rat	28	symbol	gene, protein-coding, MODEL [RefSeq]
13998950	PIK3R5	phosphoinositide-3-kinase regulatory subunit 5	ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity; G-protein beta/gamma-subunit complex binding; INVOLVED IN G protein-coupled receptor signaling pathway; phosphatidylinositol 3-kinase/protein kinase B signal transduction; positive regulation of MAP kinase activity; ... (more) PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH ataxia-oculomotor apraxia 3 (ortholog); colon cancer (ortholog); spastic ataxia (ortholog); FOUND IN cytoplasm; membrane; phosphatidylinositol 3-kinase complex, class IB; INTERACTS WITH deoxynivalenol				Pig	33	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155244600	pik3r5.L						African Clawed Frog		symbol	gene, null
155233996	pik3r5.S						African Clawed Frog		symbol	gene, null
38670308	PIK3R5-DT	PIK3R5 divergent transcript		17	8965847	8976986	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
41374674	Pik3r5l1	phosphoinositide-3-kinase, regulatory subunit 5 like 1		10	53629997	53632820	Rat		symbol , old_gene_name , PhenoGen	gene, protein-coding, MODEL [RefSeq]