| 1312063 | PGLYRP3 | peptidoglycan recognition protein 3 | This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptido glycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014] | 1 | 153297116 | 153312952 | Human | 52 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312064 | Pglyrp3 | peptidoglycan recognition protein 3 | Predicted to enable peptidoglycan binding activity; peptidoglycan immune receptor activity; and protein heterodimerization activity. Acts upstream of or within biological process involved in interaction with host; negative regulation of natural killer cell differentiation involved in immune response ; and negative regulation of type II interferon production. Predicted to be located in extracellular region. Predicted to be part of protein-containing complex. Is expressed in several structures, including adrenal gland; alimentary system; immune system; nervous system; and testis. Orthologous to human PGLYRP3 (peptidoglycan recognition protein 3). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 91919784 | 91939979 | Mouse | 74 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593164 | Pglyrp3 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits peptidoglycan binding (ortholog); peptidoglycan immune receptor activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); biological process involved in interact ion with host (ortholog); defense response to Gram-positive bacterium (ortholog); FOUND IN protein-containing complex (ortholog); INTERACTS WITH bisphenol A; methoxychlor; 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 2 | 180174931 | 180186007 | Rat | 42 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11849029 | PGLYRP3 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits N-acetylmuramoyl-L-alanine amidase activity (inferred); peptidoglycan binding (inferred); peptidoglycan immune receptor activity (inferred); INVOLVED IN biological process involved in interaction with host (ortholog); negative regulation of natural killer cell differe ntiation involved in immune response (ortholog); negative regulation of type II interferon production (ortholog); FOUND IN extracellular region (inferred); protein-containing complex (inferred) | 1 | 128642034 | 128656082 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18441089 | PGLYRP3 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits N-acetylmuramoyl-L-alanine amidase activity (inferred); peptidoglycan binding (inferred); peptidoglycan immune receptor activity (inferred); INVOLVED IN biological process involved in interaction with host (ortholog); negative regulation of natural killer cell differe ntiation involved in immune response (ortholog); negative regulation of type II interferon production (ortholog); FOUND IN extracellular region (inferred); protein-containing complex (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14140366 | PGLYRP3 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits N-acetylmuramoyl-L-alanine amidase activity (inferred); peptidoglycan binding (inferred); peptidoglycan immune receptor activity (inferred); INVOLVED IN biological process involved in interaction with host (ortholog); negative regulation of natural killer cell differe ntiation involved in immune response (ortholog); negative regulation of type II interferon production (ortholog); FOUND IN extracellular region (inferred); protein-containing complex (inferred); INTERACTS WITH zearalenone | | | | Pig | 27 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626019104 | Pglyrp3 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits peptidoglycan binding (ortholog); peptidoglycan immune receptor activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); biological process involved in interact ion with host (ortholog); defense response to Gram-positive bacterium (ortholog); FOUND IN protein-containing complex (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1591412 | Pglyrp3-ps1 | peptidoglycan recognition protein 3, pseudogene 1 | | 2 | 179201554 | 179218801 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 12628973 | LOC101970371 | peptidoglycan recognition protein 3 | ENCODES a protein that exhibits N-acetylmuramoyl-L-alanine amidase activity (inferred); peptidoglycan binding (inferred); peptidoglycan immune receptor activity (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (inferred); defense response to bacterium ( inferred); defense response to Gram-positive bacterium (inferred); FOUND IN extracellular region (inferred); protein-containing complex (inferred) | NW_004936580 | 3184904 | 3197203 | Squirrel | 16 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8719129 | LOC102006846 | peptidoglycan recognition protein 3 | | NW_004955592 | 116878 | 131316 | Chinchilla | | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |