| 734325 | Pga5 | pepsinogen 5, group I | Enables aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Is expressed in alimentary system epithelium; extraembryonic component; placenta; and stomach. Orthologous to human PGA3 (pepsinogen A3); PGA4 (pepsinogen A4); and PGA5 (pepsinogen A5). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 10646321 | 10655435 | Mouse | 45 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1350538 | PGA5 | pepsinogen A5 | This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015] | 11 | 61241175 | 61251444 | Human | 26 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 14168964 | PGA5 | pepsinogen 5, group I (pepsinogen A) | ENCODES a protein that exhibits aspartic-type endopeptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN digestion (inferred); proteolysis (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH pepstatin A | | | | Pig | 12 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11980300 | LOC100973723 | pepsinogen A5 | ASSOCIATED WITH esophagitis (ortholog) | 11 | 56539636 | 56550785 | Bonobo | 1 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12136785 | PGA | pepsinogen 5, group I (pepsinogen A) | ENCODES a protein that exhibits aspartic-type endopeptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN digestion (inferred); proteolysis (inferred); ASSOCIATED WITH esophagitis (ortholog); FOUND IN extracellular region (inferred) | 18 | 55131441 | 55140119 | Dog | 12 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 621573 | Pga3 | pepsinogen A3 | ENCODES a protein that exhibits aspartic-type endopeptidase activity (ortholog); INVOLVED IN proteolysis (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil | 1 | 216741935 | 216752067 | Rat | 44 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1345189 | PGA3 | pepsinogen A3 | This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015] | 11 | 61203515 | 61213098 | Human | 45 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1606055 | PGA4 | pepsinogen A4 | This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015] | 11 | 61222347 | 61231694 | Human | 18 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 14108631 | LOC100738961 | probable GPI-anchored adhesin-like protein PGA55 | FOUND IN nucleus (ortholog) | | | | Pig | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 18618608 | CSNK2A2IP | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog) | | | | Green Monkey | 2 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12360301 | LOC102151165 | protein FAM170A-like | | 11 | 9211765 | 9231131 | Dog | 2 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 40917145 | LOC119873860 | protein FAM170A-like | | | | | Dog | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18679602 | MEIKIN | meiotic kinetochore factor | INVOLVED IN female meiosis chromosome segregation (ortholog); homologous chromosome segregation (ortholog); male meiosis chromosome segregation (ortholog); FOUND IN condensed chromosome, centromeric region (ortholog); kinetochore (ortholog) | | | | Green Monkey | 9 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |