| 1347216 | PFN4 | profilin family member 4 | Predicted to enable actin monomer binding activity. Predicted to be involved in acrosome assembly; manchette assembly; and sperm flagellum assembly. Predicted to be located in cytoplasm. Predicted to be active in cell cortex. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 24114809 | 24123491 | Human | 40 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1359707 | Pfn4 | profilin family, member 4 | ENCODES a protein that exhibits actin binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); manchette assembly (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH acrylamide; bisphenol A; thioacetamide | 6 | 33506077 | 33516163 | Rat | 44 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1553383 | Pfn4 | profilin family, member 4 | Predicted to enable actin monomer binding activity. Involved in acrosome assembly; manchette assembly; and sperm flagellum assembly. Predicted to be located in cytoplasm. Predicted to be active in cell cortex. Is expressed in brain; ileum; and male reproductive gland or organ. Orthologous to human < span style='font-weight:700;'>PFN4 (profilin family member 4). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 4819010 | 4828813 | Mouse | 65 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8768067 | Pfn4 | profilin family member 4 | INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); manchette assembly (ortholog) | NW_004955469 | 6299451 | 6306564 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12033095 | PFN4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); actin monomer binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (inferred); cell differentiation (inferred); flagellated sperm motility (inferred); FOUND IN cell cortex (inferred); cytoplasm (inferred) | 2A | 24110565 | 24120024 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12288186 | PFN4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (inferred); cell differentiation (inferred); flagellated sperm motility (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH bisphenol A | 17 | 18571201 | 18579593 | Dog | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12685896 | Pfn4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); actin monomer binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (inferred); cell differentiation (inferred); flagellated sperm motility (inferred); FOUND IN cell cortex (inferred); cytoplasm (inferred) | NW_004936493 | 7888211 | 7891273 | Squirrel | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18665179 | PFN4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); actin monomer binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (inferred); cell differentiation (inferred); flagellated sperm motility (inferred); FOUND IN cell cortex (inferred); cytoplasm (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921074 | Pfn4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); actin monomer binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); manchette assembly (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred) | | | | Naked Mole-Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284072599 | pfn4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626001651 | Pfn4 | profilin family member 4 | INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); manchette assembly (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13924864 | PFN4 | profilin family member 4 | ENCODES a protein that exhibits actin binding (inferred); lipid binding (inferred); INVOLVED IN acrosome assembly (inferred); cell differentiation (inferred); flagellated sperm motility (inferred); FOUND IN cytoplasm (inferred) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288057289 | pfn4.S | | | | | | African Clawed Frog | | symbol | gene, null |