| 1350248 | PEX26 | peroxisomal biogenesis factor 26 | This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause o f peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2010] | 22 | 18077990 | 18105396 | Human | 251 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1557100 | Pex26 | peroxisomal biogenesis factor 26 | This gene is a member of the peroxin-26 family. The encoded protein is probably required for protein import into peroxisomes. It may anchor Pex1 and Pex6 to peroxisome membranes. Defects in a similar gene in human are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2015] | 6 | 121160176 | 121175796 | Mouse | 104 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1584998 | Pex26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (ortholog); protein-containing complex binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN protein import into peroxisome matrix (ortholog); protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog ); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 4 | 156085967 | 156099096 | Rat | 85 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8796043 | Pex26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (ortholog); protein-containing complex binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN protein import into peroxisome matrix (ortholog); protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog ); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ATPase complex (ortholog); peroxisomal membrane (ortholog); peroxisome (ortholog) | NW_004955454 | 6097251 | 6115430 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11992220 | PEX26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ATPase complex (ortholog); peroxisomal membrane (orthol og) | 22 | 1507601 | 1535859 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12308576 | PEX26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN protein import into peroxisome matrix (ortholog); protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ATPase complex (ortholog); peroxisomal membrane (ortholog); peroxisome (ortholog) | 27 | 45675537 | 45688026 | Dog | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12546461 | Pex26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (inferred); protein-containing complex binding (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein import into peroxisome matrix (inferred); protein import into peroxisome membrane (inferred); protein to membrane docking (infer red); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (inferred); peroxisome (inferred) | NW_004936807 | 1035733 | 1046225 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14162343 | PEX26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (inferred); protein-containing complex binding (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein import into peroxisome matrix (inferred); protein import into peroxisome membrane (inferred); protein to membrane docking (infer red); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (inferred); peroxisome (inferred) | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155258965 | pex26 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18901376 | Pex26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ATPase complex (ortholog); peroxisomal membrane (orthol og) | | | | Naked Mole-Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625861755 | Pex26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (ortholog); protein-containing complex binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN protein import into peroxisome matrix (ortholog); protein to membrane docking (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog ); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ATPase complex (ortholog); peroxisomal membrane (ortholog); peroxisome (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598130891 | PEX26 | peroxisomal biogenesis factor 26 | ENCODES a protein that exhibits ATPase binding (inferred); protein-containing complex binding (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein import into peroxisome matrix (inferred); protein import into peroxisome membrane (inferred); protein to membrane docking (infer red); ASSOCIATED WITH adrenoleukodystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN peroxisomal membrane (inferred); peroxisome (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259161 | pex26.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 41413514 | AC016027.6 | novel protein, PEX26-TUBA8 | ENCODES a protein that exhibits protein-containing complex binding (inferred); INVOLVED IN protein import into peroxisome membrane (inferred); FOUND IN peroxisomal membrane (inferred) | | | | Human | 3 | name | gene, protein-coding |
| 12164273 | TUBA8 | tubulin alpha 8 | ENCODES a protein that exhibits GTP binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN cytoskeleton organization (inferred); microtubule-based process (inferred); protein import into peroxisome membrane (inferred); ASSOCIATED WITH atrial fibrillation (orthol og); autosomal dominant isolated macrothrombocytopenia 2 (ortholog); Duane retraction syndrome (ortholog); FOUND IN acrosomal vesicle (inferred); cytoplasm (inferred); cytoskeleton (inferred) | 27 | 45706576 | 45725679 | Dog | 33 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |