| 1308402 | Osbpl5 | oxysterol binding protein-like 5 | ENCODES a protein that exhibits cholesterol binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); phospholipid transport (ortholog); FOUND IN endoplasmic reticulum-plasma membrane co ntact site (ortholog); transporter complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 1 | 208291441 | 208362086 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318150 | OSBPL5 | oxysterol binding protein like 5 | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like st erol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010] | 11 | 3087107 | 3165310 | Human | 109 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318151 | Osbpl5 | oxysterol binding protein-like 5 | Predicted to enable cholesterol binding activity; phosphatidylserine transfer activity; and phospholipid binding activity. Predicted to be involved in phospholipid transport. Predicted to be located in endoplasmic reticulum-plasma membrane contact site and intracellular membrane-bounded organelle. P redicted to be active in cytosol and membrane. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; immune system; and notochord. Orthologous to human OSBPL5 (oxysterol binding protein like 5). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 143242499 | 143310745 | Mouse | 106 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8868953 | Osbpl5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); phospholipid transport (ortholog); FOUND IN endoplasmic reticulum-plasma membrane co ntact site (ortholog); transporter complex (ortholog) | NW_004955422 | 14871578 | 14928935 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11969950 | OSBPL5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane phospholipid transfer (inferred); lipid transport (inferred); phosphatidylserine acyl-chain remodeling (inferred); FOUND IN endopla smic reticulum-plasma membrane contact site (ortholog) | 11 | 3097208 | 3105334 | Bonobo | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12056629 | OSBPL5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane phospholipid transfer (inferred); lipid transport (inferred); phospholipid transport (inferred); FOUND IN endoplasmic reticulum-pla sma membrane contact site (ortholog) | 18 | 47043818 | 47068277 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12598257 | Osbpl5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane phospholipid transfer (inferred); lipid transport (inferred); phospholipid transport (inferred); FOUND IN endoplasmic reticulum-pla sma membrane contact site (ortholog) | NW_004936794 | 1223573 | 1251036 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918885 | Osbpl5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); phosphatidylserine transfer activity (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); phospholipid transport (ortholog); FOUND IN endoplasmic reticulum-p lasma membrane contact site (ortholog); transporter complex (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626004334 | Osbpl5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN intermembrane phospholipid transfer (ortholog); phospholipid transport (ortholog); FOUND IN endoplasmic reticulum-plasma membrane co ntact site (ortholog); transporter complex (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18434675 | OSBPL5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane phospholipid transfer (inferred); lipid transport (inferred); phosphatidylserine acyl-chain remodeling (inferred); FOUND IN endopla smic reticulum-plasma membrane contact site (ortholog) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13901861 | OSBPL5 | oxysterol binding protein like 5 | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane phospholipid transfer (inferred); lipid transport (inferred); phospholipid transport (inferred); FOUND IN endoplasmic reticulum-pla sma membrane contact site (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |