OSBPL5 (oxysterol binding protein like 5) - Rat Genome Database

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Gene: OSBPL5 (oxysterol binding protein like 5) Chlorocebus sabaeus
Analyze
Symbol: OSBPL5
Name: oxysterol binding protein like 5
RGD ID: 18434675
Description: ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); phosphatidylinositol-4-phosphate binding (inferred); INVOLVED IN intermembrane lipid transfer (inferred); lipid transport (inferred); phospholipid transport (inferred); ASSOCIATED WITH delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum-plasma membrane contact site (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103241863; oxysterol-binding protein-related protein 5; uncharacterized LOC103241863; uncharacterized protein LOC103241863
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112,903,630 - 2,985,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12,905,931 - 2,985,474 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038100,101,809 - 100,180,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
OSBPL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112,903,630 - 2,985,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12,905,931 - 2,985,474 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038100,101,809 - 100,180,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OSBPL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38113,087,107 - 3,165,310 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl113,087,107 - 3,166,739 (-)EnsemblGRCh38hg38GRCh38
GRCh37113,108,337 - 3,186,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,064,922 - 3,143,116 (-)NCBINCBI36Build 36hg18NCBI36
Build 34113,064,921 - 3,143,116NCBI
Celera113,142,226 - 3,222,215 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef112,896,890 - 2,940,125 (-)NCBIHuRef
CHM1_1113,107,352 - 3,186,177 (-)NCBICHM1_1
T2T-CHM13v2.0113,176,307 - 3,255,561 (-)NCBIT2T-CHM13v2.0
Osbpl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,242,499 - 143,310,745 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,242,499 - 143,310,722 (-)EnsemblGRCm39 Ensembl
GRCm387143,688,762 - 143,757,008 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7143,688,762 - 143,756,985 (-)EnsemblGRCm38mm10GRCm38
MGSCv377150,874,667 - 150,927,868 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,498,152 - 143,551,353 (-)NCBIMGSCv36mm8
Celera7143,445,026 - 143,498,246 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.29NCBI
Osbpl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81208,291,441 - 208,362,086 (-)NCBIGRCr8
mRatBN7.21198,862,071 - 198,916,469 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1198,862,055 - 198,916,469 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,241,803 - 207,296,188 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,323,629 - 214,378,089 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01206,997,795 - 207,052,255 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01216,866,263 - 216,920,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,866,245 - 216,920,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,725,412 - 223,779,450 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,065,865 - 204,120,445 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11204,186,984 - 204,252,665 (-)NCBI
Celera1196,425,557 - 196,479,869 (-)NCBICelera
Cytogenetic Map1q42NCBI
Osbpl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542214,868,633 - 14,930,415 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542214,871,578 - 14,928,935 (-)NCBIChiLan1.0ChiLan1.0
OSBPL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v295,482,993 - 5,567,038 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1114,694,953 - 4,778,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0113,097,208 - 3,105,334 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1113,124,014 - 3,167,068 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl113,124,014 - 3,167,068 (-)Ensemblpanpan1.1panPan2
OSBPL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11847,043,818 - 47,068,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1847,043,829 - 47,120,907 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1845,652,860 - 45,728,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01847,725,095 - 47,801,023 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1847,724,872 - 47,801,775 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11847,168,643 - 47,244,333 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01846,752,531 - 46,828,140 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01847,498,748 - 47,574,672 (-)NCBIUU_Cfam_GSD_1.0
Osbpl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049473,280,369 - 3,333,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367941,223,726 - 1,276,614 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367941,223,573 - 1,251,036 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSBPL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl22,201,385 - 2,261,927 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.122,201,615 - 2,261,946 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22549,358 - 588,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Osbpl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476715,876,104 - 15,937,404 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476715,876,626 - 15,936,626 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 1
Low 36 17 59
Below cutoff 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000007620   ⟹   ENSCSAP00000005794
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl12,905,931 - 2,985,474 (-)Ensembl
RefSeq Acc Id: XM_008010885   ⟹   XP_008009076
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.112,903,630 - 2,985,565 (-)NCBI
Vero_WHO_p1.0NW_023666038100,101,809 - 100,180,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008010973   ⟹   XP_008009164
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.112,903,630 - 2,965,669 (-)NCBI
Vero_WHO_p1.0NW_023666038100,101,809 - 100,161,914 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008009076 (Get FASTA)   NCBI Sequence Viewer  
  XP_008009164 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005794.1
Reference Protein Sequences
RefSeq Acc Id: XP_008009076   ⟸   XM_008010885
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RB05 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008009164   ⟸   XM_008010973
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RB05 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000005794   ⟸   ENSCSAT00000007620


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009536 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007620.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2720 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.40.160.120 UniProtKB/TrEMBL
  3.30.70.3490 UniProtKB/TrEMBL
InterPro OSBP_sf UniProtKB/TrEMBL
  Oxysterol-bd UniProtKB/TrEMBL
  Oxysterol-bd_CS UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene OSBPL5 ENTREZGENE
PANTHER OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 UniProtKB/TrEMBL
  PTHR10972 UniProtKB/TrEMBL
Pfam Oxysterol_BP UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PROSITE OSBP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF144000 UniProtKB/TrEMBL
UniProt A0A0D9RB05 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 OSBPL5  oxysterol binding protein like 5  LOC103241863  uncharacterized LOC103241863  Data merged from RGD:18361118 737654 PROVISIONAL