| 3229 | Odf2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN spermatid development; centriole-centriole cohesion (ortholog); cilium organization (ortholog); FOUND IN outer dense fiber; centriolar subdistal appendage (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachloro dibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 33557738 | 33605076 | Rat | 146 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731998 | ODF2 | outer dense fiber of sperm tails 2 | The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transpor t and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers. [provided by RefSeq, Oct 2010] | 9 | 128455185 | 128501292 | Human | 145 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 736352 | Odf2 | outer dense fiber of sperm tails 2 | Predicted to enable small GTPase binding activity. Predicted to be involved in cilium organization and regulation of cilium assembly. Located in microtubule organizing center and sperm flagellum. Part of ciliary transition fiber. Is expressed in several structures, including brain; early conceptus; inner ear; liver; and reproductive system. Orthologous to human ODF2 (outer dense fiber of sperm tails 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 29779026 | 29821758 | Mouse | 176 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8746660 | Odf2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); centriole (ortholog); centrosome (ortholog) | NW_004955570 | 932002 | 966602 | Chinchilla | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11995079 | ODF2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); cilium (ortholog) | 9 | 99577891 | 99623581 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12311403 | ODF2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); cilium (ortholog) | 9 | 55060437 | 55096363 | Dog | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12533331 | Odf2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); cilium (ortholog) | NW_004936487 | 15987893 | 16029539 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18337782 | ODF2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); cilium (ortholog) | | | | Green Monkey | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257542 | odf2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14092373 | ODF2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); cilium (ortholog) | | | | Pig | 37 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626086347 | Odf2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); centriole (ortholog); centrosome (ortholog) | | | | Black Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925506 | Odf2 | outer dense fiber of sperm tails 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN centriole-centriole cohesion (ortholog); cilium organization (ortholog); intracellular protein localization (ortholog); FOUND IN centriolar subdistal appendage (ortholog); ciliary basal body (ortholog); ciliary transition f iber (ortholog) | | | | Naked Mole-Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257431 | odf2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 10450389 | ODF2-AS1 | ODF2 antisense RNA 1 | INTERACTS WITH sodium arsenite | 9 | 128468925 | 128473012 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 733828 | ODF1 | outer dense fiber of sperm tails 1 | The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transpor t and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008] | 8 | 102551589 | 102561018 | Human | 47 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1318144 | Odf2l | outer dense fiber of sperm tails 2-like | Involved in negative regulation of cilium assembly. Predicted to be located in centriolar satellite. Predicted to be active in centrosome and ciliary basal body. Orthologous to human ODF2L (outer dense fiber of sperm tails 2 like). [provided by Alliance of Genom e Resources, Jul 2025] | 3 | 144824330 | 144859676 | Mouse | 83 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593831 | Odf2l | outer dense fiber of sperm tails 2-like | INVOLVED IN negative regulation of cilium assembly (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; bromobenzene | 2 | 236696158 | 236733090 | Rat | 75 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1606519 | ODF2L | outer dense fiber of sperm tails 2 like | Involved in negative regulation of cilium assembly. Located in centriolar satellite and ciliary basal body. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 86346837 | 86396323 | Human | 74 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8960907 | Odf2l | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog) | NW_004955423 | 7777791 | 7819095 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11797899 | ODF2L | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); regulation of cilium assembly (inferred); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | 1 | 118879250 | 118927519 | Bonobo | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12350900 | ODF2L | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | 6 | 61637855 | 61779337 | Dog | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12537331 | Odf2l | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); regulation of cilium assembly (inferred); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | NW_004936865 | 252865 | 290595 | Squirrel | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926481 | Odf2l | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); regulation of cilium assembly (inferred); FOUND IN centriolar satellite (ortholog) | | | | Naked Mole-Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626068256 | Odf2l | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18394685 | ODF2L | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); regulation of cilium assembly (inferred); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | | | | Green Monkey | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14110922 | ODF2L | outer dense fiber of sperm tails 2 like | INVOLVED IN negative regulation of cilium assembly (inferred); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | | | | Pig | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250632 | odf2l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155249304 | odf2l.L | | | | | | African Clawed Frog | | symbol | gene, null |