| 1305766 | Nudt21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); mRNA alternative poly adenylation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum | 19 | 10980797 | 10996903 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313996 | NUDT21 | nudix hydrolase 21 | The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other process ing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008] | 16 | 56429133 | 56451332 | Human | 162 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552286 | Nudt21 | nudix hydrolase 21 | Enables chromatin binding activity. Involved in positive regulation of pro-B cell differentiation; positive regulation of stem cell differentiation; and post-transcriptional regulation of gene expression. Located in nucleus. Is expressed in several structures, including alimentary system; central ne rvous system; early embryo; respiratory system; and sensory organ. Orthologous to human NUDT21 (nudix hydrolase 21). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 94746031 | 94763667 | Mouse | 170 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8759834 | Nudt21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); mRNA alternative poly adenylation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog) | NW_004955433 | 14220356 | 14234423 | Chinchilla | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11738350 | NUDT21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (inferred); histone deacetylase binding (inferred); identical protein binding (inferred); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); mRNA alternative poly adenylation (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); mRNA cleavage and polyadenylation specificity factor complex (inferred) | 16 | 36715373 | 36737593 | Bonobo | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12089225 | NUDT21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (inferred); histone deacetylase binding (inferred); identical protein binding (inferred); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); mRNA alternative poly adenylation (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); mRNA cleavage and polyadenylation specificity factor complex (inferred) | 2 | 59736739 | 59751967 | Dog | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12604430 | Nudt21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (inferred); histone deacetylase binding (inferred); identical protein binding (inferred); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); mRNA alternative poly adenylation (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); mRNA cleavage and polyadenylation specificity factor complex (inferred) | NW_004936475 | 8739992 | 8759165 | Squirrel | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625866742 | Nudt21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); mRNA alternative poly adenylation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog) | | | | Black Rat | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13953905 | NUDT21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA alternative polyadenylation (ortholog); positive re gulation of pro-B cell differentiation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); nuclear body (ortholog) | | | | Pig | 66 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18437547 | NUDT21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (inferred); histone deacetylase binding (inferred); identical protein binding (inferred); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); mRNA alternative poly adenylation (inferred); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); mRNA cleavage and polyadenylation specificity factor complex (inferred) | | | | Green Monkey | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234300 | nudt21 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18909044 | Nudt21 | nudix hydrolase 21 | ENCODES a protein that exhibits chromatin binding (ortholog); histone deacetylase binding (ortholog); identical protein binding (ortholog); INVOLVED IN co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (ortholog); mRNA alternative polyadenylation (ortholog); positive re gulation of pro-B cell differentiation (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); FOUND IN centrosome (ortholog); mRNA cleavage and polyadenylation specificity factor complex (ortholog); nuclear body (ortholog) | | | | Naked Mole-Rat | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155236846 | nudt21.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16568285 | AL445647.2 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 (NUDT21) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 4891984 | NUDT21P1 | nudix hydrolase 21 pseudogene 1 | | 13 | 87765607 | 87766196 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |