| 1307331 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits nicotinamide-nucleotide adenylyltransferase activity (ortholog); nicotinate-nucleotide adenylyltransferase activity (ortholog); protein ADP-ribosyltransferase-substrate adaptor activity (ortholog); INVOLVED IN cellular response to angiotensin; NAD+ biosynthetic proces s; 'de novo' NAD+ biosynthetic process from L-tryptophan (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH hypertrophic cardiomyopathy; genetic disease (ortholog); vascular dementia (ortholog); FOUND IN cytosol (ortholog); extrinsic component of membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bis(2-ethylhexyl) phthalate | 13 | 67655794 | 67831609 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316464 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 1 | 183248237 | 183418380 | Human | 146 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552668 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | Enables nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Involved in nicotinamide metabolic process; nicotinamide nucleotide biosynthetic process; and nicotinamide riboside metabolic process. Located in cytoplasmic vesicle; synapse; and tra ns-Golgi network. Is extrinsic component of membrane. Is active in cytosol. Is expressed in alimentary system; nervous system; and sensory organ. Orthologous to human NMNAT2 (nicotinamide nucleotide adenylyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 152830532 | 152995012 | Mouse | 210 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8946683 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits nicotinamide-nucleotide adenylyltransferase activity (ortholog); nicotinate-nucleotide adenylyltransferase activity (ortholog); protein ADP-ribosyltransferase-substrate adaptor activity (ortholog); INVOLVED IN 'de novo' NAD+ biosynthetic process from L-tryptophan (ort holog); cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN cytosol (ortholog); extrinsic component of membrane (ortholog); Golgi apparatus (ortholog) | NW_004955406 | 22077247 | 22274668 | Chinchilla | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12002032 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); nicotinamide-nucleotide adenylyltransferase activity (inferred); INVOLVED IN cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleo tide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN axon (inferred); cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred) | 1 | 158768949 | 158948711 | Bonobo | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12308990 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits adenylyltransferase activity (inferred); ATP binding (inferred); catalytic activity (inferred); INVOLVED IN cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathwa y; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN axon (inferred); cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred) | 7 | 16626213 | 16819681 | Dog | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12533384 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); nicotinamide-nucleotide adenylyltransferase activity (inferred); INVOLVED IN cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleo tide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN axon (inferred); cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred) | NW_004936481 | 6443286 | 6585784 | Squirrel | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18651066 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); nicotinamide-nucleotide adenylyltransferase activity (inferred); INVOLVED IN cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleo tide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN axon (inferred); cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred) | | | | Green Monkey | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626030557 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits nicotinamide-nucleotide adenylyltransferase activity (ortholog); nicotinate-nucleotide adenylyltransferase activity (ortholog); protein ADP-ribosyltransferase-substrate adaptor activity (ortholog); INVOLVED IN 'de novo' NAD+ biosynthetic process from L-tryptophan (ort holog); cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN cytosol (ortholog); extrinsic component of membrane (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909490 | Nmnat2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits protein ADP-ribosyltransferase-substrate adaptor activity (ortholog); INVOLVED IN 'de novo' NAD+ biosynthetic process from L-tryptophan (ortholog); cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN cytosol (ortholog); extrinsic component of membrane (ortholog); late endosome (ortholog) | | | | Naked Mole-Rat | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14123011 | NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); nicotinamide-nucleotide adenylyltransferase activity (inferred); INVOLVED IN cellular response to angiotensin (ortholog); NAD+ biosynthetic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleo tide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH genetic disease (ortholog); hypertrophic cardiomyopathy (ortholog); vascular dementia (ortholog); FOUND IN axon (inferred); cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245756 | nmnat2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155245755 | nmnat2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248756 | nmnat2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16572997 | AL354953.1 | novel transcript, antisense to NMNAT2 | | | | | Human | | name | gene, lncrna |
| 16571488 | AL449223.1 | novel transcript, antisense to NMNAT2 | | | | | Human | | name | gene, lncrna |