| 1308301 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 68331609 | 68342562 | Rat | 99 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1552972 | Nle1 | notchless homolog 1 | Acts upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and positive regulation of canonical Wnt signaling pathway. Located in nucleolus. Is expressed in several structures, including 2-cell stage embryo; gonad; hemolymphoid system gland; inner cell mass; and liver. Orthologous to human NLE1 (notchless homolog 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 82791594 | 82799272 | Mouse | 128 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604007 | NLE1 | notchless homolog 1 | Predicted to be involved in regulation of Notch signaling pathway. Predicted to act upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and positive regulation of canonical Wnt signaling pathway. Located in nucleolus and nucleoplasm . [provided by Alliance of Genome Resources, Jul 2025] | 17 | 35128730 | 35142303 | Human | 101 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8895620 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (ortholog) | NW_004955481 | 9821329 | 9830350 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12041092 | NLE1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (inferred); nucleus (inferred) | 17 | 21643865 | 21654169 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12420550 | NLE1 | notchless homolog 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); F OUND IN centrosome (inferred); chromosome, telomeric region (inferred); nucleolus (inferred) | 9 | 38222083 | 38230819 | Dog | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12506597 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (inferred) | NW_004936538 | 101245 | 109796 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18650037 | NLE1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14081082 | NLE1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256278 | nle1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626156134 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936808 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (inferred) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256279 | nle1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 12087896 | RAD51D | RAD51 paralog D | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN chromosome organization (ortholog); DNA damage response (ortholog); interstrand cross-link repair (ortholog); PARTICIPATES IN hom ologous recombination pathway of double-strand break repair; ASSOCIATED WITH breast cancer (ortholog); Chromosome Deletion (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog) | 9 | 38242178 | 38259788 | Dog | 107 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12300513 | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase | ENCODES a protein that exhibits p53 binding (ortholog); protease binding (ortholog); protein kinase binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of s ignal transduction by p53 class mediator (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); endosome membrane (ortholog) | 9 | 38271419 | 38346103 | Dog | 71 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |