| 1308624 | Neu4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN ganglioside catabolic process (ortholog); glycoprotein catabolic process (ortholog); negative regulation of neuron projection development (ortholog); PARTICIPATES IN sphingolipid metabolic pathway; FOUND IN endoplas mic reticulum membrane (ortholog); lysosome (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH acrylamide; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 9 | 101844261 | 101849917 | Rat | 77 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318506 | NEU4 | neuraminidase 4 | The protein encoded by this gene belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Alternatively spliced transcript variants encoding different isoforms ha ve been noted for this gene. [provided by RefSeq, Nov 2009] | 2 | 241809193 | 241817413 | Human | 82 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318507 | Neu4 | sialidase 4 | Enables exo-alpha-sialidase activity. Involved in ganglioside catabolic process; glycoprotein catabolic process; and negative regulation of neuron projection development. Located in neuron projection and plasma membrane. Is expressed in brain; liver; lung; metanephros; and spleen. Orthologous to hum an NEU4 (neuraminidase 4). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 93948215 | 93956056 | Mouse | 96 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8933040 | Neu4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN ganglioside catabolic process (ortholog); glycoprotein catabolic process (ortholog); negative regulation of neuron projection development (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); lysosome (ort holog); mitochondrial inner membrane (ortholog) | NW_004955542 | 66214 | 70456 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11725225 | NEU4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); FOUND IN lysosome (ortholog) | 12 | 130824179 | 130833287 | Bonobo | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12287686 | NEU4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); galactosylceramide sulfotransferase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); FOUND IN lysosome (ortholog) | 25 | 51594865 | 51602500 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12565389 | Neu4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN ganglioside catabolic process (ortholog); glycoprotein catabolic process (ortholog); negative regulation of neuron projection development (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); lysosome (ort holog); mitochondrial inner membrane (ortholog) | NW_004936745 | 172983 | 175470 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238206 | neu4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18634247 | NEU4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN ganglioside catabolic process (inferred); glycoprotein catabolic process (inferred); lipid catabolic process (inferred); FOUND IN lysosome (ortholog) | | | | Green Monkey | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919696 | Neu4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); FOUND IN lysosome (ortholog); organelle inner membrane (orthol og) | | | | Naked Mole-Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14048904 | NEU4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN ganglioside catabolic process (inferred); glycoprotein catabolic process (inferred); lipid catabolic process (inferred); FOUND IN lysosome (ortholog) | | | | Pig | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625994859 | Neu4 | neuraminidase 4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (ortholog); INVOLVED IN ganglioside catabolic process (ortholog); glycoprotein catabolic process (ortholog); negative regulation of neuron projection development (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); lysosome (ort holog); mitochondrial inner membrane (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231155 | neu4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155238205 | neu4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 32729420 | LOC117979510 | sialidase-4 | ENCODES a protein that exhibits exo-alpha-sialidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN ganglioside catabolic process (inferred); glycoprotein catabolic process (inferred); lipid catabolic process (inferred); FOUND IN cytoplasm (inferred); endoplasmic reticulum membrane (inferred); lysosomal lumen (inferred) | 2B | 129087519 | 129093811 | Bonobo | 27 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |