| 1310053 | Ndfip1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); ASSOCIATED WITH stroke; Hereditary Neoplastic Syndromes (ortho log); FOUND IN cell cortex (ortholog); Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; alpha-Zearalanol | 18 | 30516931 | 30567199 | Rat | 118 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320732 | NDFIP1 | Nedd4 family interacting protein 1 | The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008] | 5 | 142108779 | 142154440 | Human | 112 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320733 | Ndfip1 | Nedd4 family interacting protein 1 | Enables WW domain binding activity. Acts upstream of or within several processes, including negative regulation of interleukin-4 production; negative regulation of type 2 immune response; and regulation of lymphocyte activation. Located in Golgi apparatus and cell cortex. Is expressed in several str uctures, including alimentary system; nervous system; retina; and rib. Orthologous to human NDFIP1 (Nedd4 family interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 18 | 38551960 | 38598250 | Mouse | 158 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8969136 | Ndfip1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); st roke (ortholog); FOUND IN cell cortex (ortholog); Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004955415 | 11643846 | 11666131 | Chinchilla | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11688713 | NDFIP1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); negative regulation of isotype switching to IgE isotypes (ortholog); ASSOCIATED WITH Hereditary Neoplastic Sy ndromes (ortholog); stroke (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); endomembrane system (inferred) | 5 | 137467161 | 137511569 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12206926 | NDFIP1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); negative regulation of isotype switching to IgE isotypes (ortholog); ASSOCIATED WITH Hereditary Neoplastic Sy ndromes (ortholog); stroke (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); endomembrane system (inferred) | 2 | 36978148 | 37065247 | Dog | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12732888 | Ndfip1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); st roke (ortholog); FOUND IN cell cortex (ortholog) | NW_004936504 | 12053470 | 12103346 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14262603 | NDFIP1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); negative regulation of isotype switching to IgE isotypes (ortholog); ASSOCIATED WITH Hereditary Neoplastic Sy ndromes (ortholog); stroke (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); endomembrane system (inferred) | | | | Pig | 39 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18932864 | Ndfip1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); st roke (ortholog); FOUND IN cell cortex (ortholog) | | | | Naked Mole-Rat | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626100310 | Ndfip1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); ASSOCIATED WITH stroke (ortholog); FOUND IN cell cortex (ortho log); Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18756469 | NDFIP1 | Nedd4 family interacting protein 1 | ENCODES a protein that exhibits WW domain binding (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); negative regulation of interleukin-4 production (ortholog); negative regulation of isotype switching to IgE isotypes (ortholog); ASSOCIATED WITH Hereditary Neoplastic Sy ndromes (ortholog); stroke (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); endomembrane system (inferred) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250233 | ndfip1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155246362 | ndfip1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259285 | ndfip1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 8549095 | NDFIP1P1 | Nedd4 family interacting protein 1 pseudogene 1 | | 12 | 18358433 | 18359144 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |