| 1307193 | Myo10 | myosin X | ENCODES a protein that exhibits actin filament binding (ortholog); microfilament motor activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN cytoskeleton-dependent intracellular transport (ortholog); positive regulation of cell-cell adhesion (ortholog); regula tion of cell shape (ortholog); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cytosol (ortholog); filopodium (ortholog); filopodium tip (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 77831532 | 78036137 | Rat | 199 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1316238 | MYO10 | myosin X | This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class membe rs by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011] | 5 | 16661907 | 16936288 | Human | 197 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316239 | Myo10 | myosin X | Predicted to enable cytoskeletal protein binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Acts upstream of or within positive regulation of cell-cell adhesion. Located in filopodium; neuron projection; and neuronal cell body. Is expressed in several structures, including autopod; central nervous system; genitourinary system; gut; and integumental system placode. Orthologous to human MYO10 (myosin X). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 25622636 | 25813759 | Mouse | 237 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8971709 | Myo10 | myosin X | ENCODES a protein that exhibits spectrin binding (ortholog); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); regulation of cell shape (ortholog); regulation of filopodium assembly (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cytosol (ortholog); filopodium (ortholog) ; neuron projection (ortholog) | NW_004955426 | 5725766 | 5885316 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11753780 | MYO10 | myosin X | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN neuron projection (ortholog); neuronal cell body (ortholog) | 5 | 16969146 | 17239732 | Bonobo | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12398144 | MYO10 | myosin X | ENCODES a protein that exhibits actin binding (inferred); ATP binding (inferred); calmodulin binding (inferred); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cell cortex (inferred); cytoskeleton (inferred); cytosol (inferred) | 4 | 86701907 | 86792432 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12725523 | Myo10 | myosin X | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cell cortex (inferred); cytoskeleton (inferred); cytosol (inferred) | NW_004936480 | 19280723 | 19443267 | Squirrel | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14155282 | MYO10 | myosin X | ENCODES a protein that exhibits actin binding (inferred); ATP binding (inferred); calmodulin binding (inferred); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cell cortex (inferred); cytoskeleton (inferred); cytosol (inferred); INT ERACTS WITH chlorpyrifos; resveratrol | | | | Pig | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932130 | Myo10 | myosin X | ENCODES a protein that exhibits spectrin binding (ortholog); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cytosol (ortholog); neuron projection (ortholog); neuronal cell body (ortholog) | | | | Naked Mole-Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18698361 | MYO10 | myosin X | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); cytoskeleton (inferred ) | | | | Green Monkey | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625883697 | Myo10 | myosin X | ENCODES a protein that exhibits spectrin binding (ortholog); INVOLVED IN positive regulation of cell-cell adhesion (ortholog); regulation of cell shape (ortholog); regulation of filopodium assembly (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN cytosol (ortholog); filopodium (ortholog) ; neuron projection (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246374 | myo10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 283964657 | myo10.2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405857984 | myo10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861271 | myo10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862134 | myo10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863903 | myo10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469677 | myo10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626181564 | myo10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856348 | myo10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862890 | myo10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859017 | myo10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859338 | myo10.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 283964984 | myo10.2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284120706 | myo10.2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14384374 | Myo10A | | | | | | Fly | | symbol | gene, null |
| 1353980 | MYH10 | myosin heavy chain 10 | This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regula tion of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] | 17 | 8474212 | 8630725 | Human | 315 | description | gene, protein-coding, REVIEWED [RefSeq] |
