| 1308474 | Mybl2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of neuron a poptotic process; cellular response to leukemia inhibitory factor (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate; 17beta-estradiol | 3 | 172124765 | 172153221 | Rat | 193 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318263 | MYBL2 | MYB proto-oncogene like 2 | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repre ssor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] | 20 | 43667114 | 43716482 | Human | 202 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318264 | Mybl2 | Myb proto-oncogene like 2 | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor and mitotic spindle assembly. Located in nucleus . Part of Myb complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system; and skin. Used to study acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human MYBL2 (MYB proto-oncogene like 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 162896246 | 162926608 | Mouse | 249 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8713691 | Mybl2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to leukemia i nhibitory factor (ortholog); mitotic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955445 | 13496919 | 13530689 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11709935 | MYBL2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitot ic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 20 | 40005482 | 40053324 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12085328 | MYBL2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitot ic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (inferred); nucleoplasm (inferred); nucleus (inferred) | 24 | 31339570 | 31382626 | Dog | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12572137 | Mybl2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitot ic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936530 | 2918924 | 2953467 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234260 | mybl2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625997371 | Mybl2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to leukemia i nhibitory factor (ortholog); mitotic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14191867 | MYBL2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitot ic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 28 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18523235 | MYBL2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitot ic spindle assembly (ortholog); positive regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922167 | Mybl2 | MYB proto-oncogene like 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mitotic spindle assembly (ortholog); positive regulat ion of neuron apoptotic process (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN Myb complex (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231601 | mybl2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155234259 | mybl2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16559089 | AC093853.1 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 (MYBL2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |