| 1562333 | Mreg | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome localization (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); late endosome membrane (ortholog); melanosome (orth olog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 81236019 | 81291601 | Rat | 119 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1604338 | MREG | melanoregulin | Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in melanocyte differentiation; melanosome transport; and phagosome maturation. Predicted to act upstream of or within developmental pigmentation. Predicted to be located in late endosome membrane and melanosome membr ane. Predicted to be part of protein-containing complex. Predicted to be active in melanosome. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 215939308 | 216034096 | Human | 121 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1621189 | Mreg | melanoregulin | Enables phosphatidylinositol binding activity. Involved in melanosome localization; minus-end-directed organelle transport along microtubule; and phagosome maturation. Acts upstream of or within melanocyte differentiation and melanosome transport. Located in late endosome membrane and melanosome mem brane. Part of protein-containing complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; inner ear; and liver. Orthologous to human MREG (melanoregulin). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 72198392 | 72251418 | Mouse | 124 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8779353 | Mreg | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome localization (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); late endosome membrane (ortholog); melanosome (orth olog) | NW_004955457 | 9534 | 78617 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11746748 | MREG | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome transport (ortholog); FOUND IN cytoplasmic vesicle membrane (inferred); late endosome membrane (inferred); melanosome (inferre d) | 2B | 103204959 | 103296122 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12391161 | MREG | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome transport (ortholog); FOUND IN cytoplasmic vesicle membrane (inferred); late endosome membrane (inferred); melanosome (inferre d) | 37 | 22958890 | 22999955 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12494777 | Mreg | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome transport (ortholog); FOUND IN cytoplasmic vesicle membrane (inferred); late endosome membrane (inferred); melanosome (inferre d) | NW_004936586 | 1203520 | 1261341 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18606604 | MREG | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome transport (ortholog); FOUND IN cytoplasmic vesicle membrane (inferred); late endosome membrane (inferred); melanosome (inferre d) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908361 | Mreg | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome localization (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); late endosome membrane (ortholog); melanosome membr ane (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625902299 | Mreg | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome localization (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); late endosome membrane (ortholog); melanosome (orth olog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14150179 | MREG | melanoregulin | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN developmental pigmentation (ortholog); melanocyte differentiation (ortholog); melanosome transport (ortholog); FOUND IN cytoplasmic vesicle membrane (inferred); late endosome membrane (inferred); melanosome (inferre d); INTERACTS WITH deoxynivalenol | | | | Pig | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231975 | mreg | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155232007 | mreg.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155231976 | mreg.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 10400307 | MREGP1 | melanoregulin pseudogene 1 | | 12 | 31254361 | 31254445 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |