Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Demecolcine results in increased expression of MREG mRNA | CTD | PMID:23649840 | 1-naphthyl isothiocyanate | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of MREG mRNA | CTD | PMID:30723492 | 17beta-estradiol | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | EGF protein promotes the reaction [Estradiol results in increased expression of MREG mRNA] | CTD | PMID:24758408 | 17beta-estradiol | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of MREG mRNA | CTD | PMID:32145629 | 17beta-estradiol | affects expression | ISO | MREG (Homo sapiens) | 6480464 | Estradiol affects the expression of MREG mRNA | CTD | PMID:22574217 | 17beta-estradiol | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Estradiol results in increased expression of MREG mRNA | CTD | PMID:21795739 and PMID:24758408 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | MREG (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:23146750 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MREG mRNA | CTD | PMID:21570461 and PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MREG mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MREG mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of MREG mRNA | CTD | PMID:25975270 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of MREG mRNA | CTD | PMID:25172293 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of MREG mRNA | CTD | PMID:33297965 | acetamide | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of MREG mRNA | CTD | PMID:31881176 | afimoxifene | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in increased expression of MREG mRNA] | CTD | PMID:21233418 | aflatoxin B1 | affects expression | ISO | MREG (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of MREG protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | MREG (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of MREG intron | CTD | PMID:30157460 | aflatoxin B1 | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of MREG mRNA | CTD | PMID:22100608 and PMID:32234424 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MREG mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MREG mRNA | CTD | PMID:33167477 | arsenite(3-) | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to MREG mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of MREG mRNA | CTD | PMID:19770486 and PMID:21715664 | benzo[a]pyrene | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MREG mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | MREG (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MREG intron | CTD | PMID:30157460 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Benzo[k]fluoranthene | decreases expression | EXP | | 6480464 | benzo(k)fluoranthene results in decreased expression of MREG mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MREG mRNA | CTD | PMID:21932408 | bisphenol A | increases methylation | ISO | MREG (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of MREG gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of MREG mRNA | CTD | PMID:32145629 | bisphenol A | affects expression | ISO | Mreg (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of MREG mRNA | CTD | PMID:25181051 and PMID:30903817 | calcitriol | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Calcitriol results in increased expression of MREG mRNA | CTD | PMID:26485663 | cantharidin | decreases expression | EXP | | 6480464 | Cantharidin results in decreased expression of MREG mRNA | CTD | PMID:36907384 | carbamazepine | affects expression | ISO | MREG (Homo sapiens) | 6480464 | Carbamazepine affects the expression of MREG mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | carbon nanotube | increases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Nanotubes and Carbon results in increased expression of MREG mRNA | CTD | PMID:24911292 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MREG gene] | CTD | PMID:28238834 | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of MREG mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of MREG mRNA | CTD | PMID:37019170 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MREG gene | CTD | PMID:20938992 | copper(II) sulfate | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of MREG mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MREG mRNA | CTD | PMID:25562108 | epoxiconazole | affects expression | EXP | | 6480464 | epoxiconazole affects the expression of MREG mRNA | CTD | PMID:35436446 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MREG gene | CTD | PMID:20938992 | FR900359 | decreases phosphorylation | ISO | MREG (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of MREG protein | CTD | PMID:37730182 | furan | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | furan results in decreased expression of MREG mRNA | CTD | PMID:25539665 and PMID:26194646 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of MREG mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MREG gene | CTD | PMID:20938992 | leflunomide | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | leflunomide results in decreased expression of MREG mRNA | CTD | PMID:28988120 | lipopolysaccharide | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of MREG mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MREG mRNA] | CTD | PMID:35811015 | methyl methanesulfonate | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of MREG mRNA | CTD | PMID:23649840 | p-toluidine | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | 4-toluidine results in decreased expression of MREG mRNA | CTD | PMID:27638505 | paracetamol | decreases expression | ISO | MREG (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MREG mRNA | CTD | PMID:29067470 | paracetamol | increases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of MREG mRNA | CTD | PMID:33387578 | parathion | decreases expression | EXP | | 6480464 | Parathion results in decreased expression of MREG mRNA | CTD | PMID:34813904 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of MREG mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of MREG mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of MREG mRNA | CTD | PMID:23091169 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of MREG mRNA | CTD | PMID:28903501 | protein kinase inhibitor | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of MREG mRNA] | CTD | PMID:28003376 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | MREG (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MREG mRNA] | CTD | PMID:35811015 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of MREG mRNA | CTD | PMID:29341224 | sodium arsenite | increases expression | ISO | MREG (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MREG mRNA | CTD | PMID:34032870 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of MREG mRNA | CTD | PMID:37682722 | tetrachloroethene | increases expression | EXP | | 6480464 | Tetrachloroethylene results in increased expression of MREG mRNA | CTD | PMID:28973375 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of MREG mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MREG mRNA | CTD | PMID:27339419 and PMID:31919559 | thioacetamide | decreases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of MREG mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of MREG mRNA | CTD | PMID:23409001 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of MREG mRNA | CTD | PMID:29264374 | trichloroethene | increases expression | ISO | Mreg (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of MREG mRNA | CTD | PMID:33387578 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of MREG mRNA | CTD | PMID:32835833 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of MREG mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | MREG (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MREG mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | MREG (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MREG mRNA | CTD | PMID:19101580 and PMID:27188386 | vorinostat | increases expression | ISO | MREG (Homo sapiens) | 6480464 | vorinostat results in increased expression of MREG mRNA | CTD | PMID:27188386 | zoledronic acid | increases expression | ISO | MREG (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of MREG mRNA | CTD | PMID:20977926 | 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